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Abstract
Pain has been reported to be a common problem in the general population and end-stage renal disease (ESRD) patients. Although similar data for pre-ESRD patients are lacking, we recently reported that the prevalence of pain is also very high (>70%) among pre-ESRD patients at a Los Angeles County tertiary referral centre. The high prevalence of pain in the CKD population is particularly concerning because pain has been shown to be associated with poor quality of life. Of greater concern, poor quality of life, at least in dialysis patients, has been shown to be associated with poor survival. We herein discuss the pathophysiology of common pain conditions, review a commonly accepted approach to the management of pain in the general population, and discuss analgesic-induced renal complications and therapeutic issues specific for patients with reduced renal function.
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Details
1 Nephrology Division, Department of Medicine, Olive View-UCLA Medical Center, Sylmar
2 Department of Medicine, Greater Los Angeles VA Medical Center, Los Angeles
3 Mercy General Hospital, Sacramento
4 Cardiology Division, Good Samaritan Hospital/Harbor-UCLA Medical Center, Los Angeles
5 David Geffen School of Medicine at UCLA, Kidney and Pancreas Transplant Program, Los Angeles, CA, USA