Abstract

Gastric cancer is the fifth most prevalent cancer worldwide and the third leading cause of cancer- related mortality. Peritoneal carcinomatosis can develop in patients with a primary gastric tumor in a substantial proportion of patients, with estimates ranging from 14% to 43%. For patients with peritoneal carcinomatosis from gastric cancer, therapeutic options are limited. Intraperitoneal chemotherapy, combined with hyperthermia (HIPEC), provides regional dose intensification within the peritoneal cavity, effectively targeting peritoneal carcinomatosis with minimal systemic exposure. We report a case of gastroesophageal junction adenocarcinoma with peritoneal metastasis successfully treated with of cytoreductive surgery and HIPEC, and followed by surgery and systemic chemotherapy, highlighting HIPEC as one of the viable options and the importance of a multimodal approach for the treatment of this case.

Details

Title
Role of cytoreduction and hyperthermic intraperitoneal chemotherapy for metastatic gastroesophageal junction adenocarcinoma?
Author
Zaidi, Syed M H 1 ; Ho, Kimberly 2   VIAFID ORCID Logo  ; Sohail, Amir H 2 ; Whittington, Jennifer 2 

1  King Edward Medical University, Department of Medicine , Lahore , Pakistan 
2  NYU Long Island School of Medicine, Department of Surgery , Mineola, NY , United States 
Publication year
2023
Publication date
Dec 2023
Publisher
Oxford University Press
e-ISSN
20428812
Source type
Scholarly Journal
Language of publication
English
DOI
https://doi.org/10.1093/jscr/rjad664
ProQuest document ID
3170752031
Copyright
Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2023. This work is published under https://creativecommons.org/licenses/by-nc/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.