Content area
Abstract
Using heavy-ion microbeam, we report target irradiation of selected compartments within the diapause-terminated egg and its mutational consequences in the silkworm, Bombyx mori. On one hand, carbon-ion exposure of embryo to 0.5-6 Gy increased the somatic mutation frequency, suggesting targeted radiation effects. On the other, such increases were not observed when yolk was targeted, suggesting a lack of nontargeted bystander effect.
Details
Title
Targeted Heavy-Ion Microbeam Irradiation of the Embryo But Not Yolk in the Diapause-Terminated Egg of the Silkworm, Bombyx mori, Induces The Somatic Mutation
Author
Furusawa, Toshiharu 1 ; Fukamoto, Kana 2 ; Sakashita, Tetsuya 2 ; Suzuki, Eiko 1 ; Kakizaki, Takehiko 3 ; Hamada, Nobuyuki 4 ; Funayama, Tomoo 2 ; Suzuki, Hiromi 5 ; Ishioka, Noriaki 6 ; Wada, Seiichi 3 ; Kobayashi, Yasuhiko 2 ; Nagaoka, Shunji 7
1 Department of Applied Biology, Faculty of Textile Science, Kyoto Institute of Technology, Matsugasaki, Sakyo-ku, Kyoto 606-8585, Japan
2 Microbeam Radiation Biology Group, Japan Atomic Energy Agency, 1233 Watanuki-machi, Takasaki, Gunma 370-1292, Japan
3 Department of Veterinary Medicine, Kitasato University Graduate School of Veterinary Medicine and Animal Sciences, 23-35-1 Higashi, Towada, Aomori 034-8628, Japan
4 Department of Pathology, Institute of Development, Aging and Cancer, Tohoku University, 4-1 Seiryo-machi, Sendai 980-8575, Japan
5 Japan Space Forum, 2-2-1 Sengen, Tsukuba, Ibaraki 305-8505, Japan
6 Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency, 2-1-1 Sengen, Tsukuba, Ibaraki 305-8505, Japan
7 School of Health Science, Fujita Health University, Toyoake, Aichi 470-110, Japan
1 Department of Applied Biology, Faculty of Textile Science, Kyoto Institute of Technology, Matsugasaki, Sakyo-ku, Kyoto 606-8585, Japan
2 Microbeam Radiation Biology Group, Japan Atomic Energy Agency, 1233 Watanuki-machi, Takasaki, Gunma 370-1292, Japan
3 Department of Veterinary Medicine, Kitasato University Graduate School of Veterinary Medicine and Animal Sciences, 23-35-1 Higashi, Towada, Aomori 034-8628, Japan
4 Department of Pathology, Institute of Development, Aging and Cancer, Tohoku University, 4-1 Seiryo-machi, Sendai 980-8575, Japan
5 Japan Space Forum, 2-2-1 Sengen, Tsukuba, Ibaraki 305-8505, Japan
6 Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency, 2-1-1 Sengen, Tsukuba, Ibaraki 305-8505, Japan
7 School of Health Science, Fujita Health University, Toyoake, Aichi 470-110, Japan
Pages
371-375
Publication year
2009
Publication date
Jul 2009
ISSN
04493060
e-ISSN
13499157
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
3170889817
Copyright
Copyright © 2009 Japan Radiation Research Society.