Abstract

We conducted a retrospective analysis of 38 children and youth with human immunodeficiency virus (aged 0–19 years) in the United States and report an increased rate of change of BMI-for-age z score after initiating integrase strand transfer inhibitors (+0.19 z score units/year [95% confidence interval, .01–.37]; P = .036) for a median follow-up of 527.5 days.

Details

Title
Integrase Strand Transfer Inhibitors and Weight Gain in Children and Youth With Perinatal Human Immunodeficiency Virus in the DC Cohort
Author
Koay, Wei Li A 1   VIAFID ORCID Logo  ; Dirajlal-Fargo, Sahera 2 ; Levy, Matthew E 3 ; Kulie, Paige 4 ; Monroe, Anne 4 ; Castel, Amanda D 4 ; Rakhmanina, Natella Y 5 ; Lawrence D’Angelo; Natella Rakhmanina; Kharfen, Michael; Serlin, Michael; Kumar, Princy; Bamdad, Aria; Bezabeh, Tsedenia; Pamela Katzen Burrows; Reamer, Susan; Sapozhnikova, Alla; Temprosa, Marinella; Younes, Naji; Byrne, Morgan; Castel, Amanda; Greenberg, Alan; Jaurretche, Maria; Levy, Matthew; Peterson, James; Lindsey Powers Happ; Wilbourn, Brittany; Ma, Yan; Akselrod, Hana; Wilcox, Ronald; Rana, Sohail; Horberg, Michael; Fernandez, Ricardo; Hebou, Annick; Dieffenbach, Carl; Masur, Henry; Bordon, Jose; Gebeyehu Teferi; Benator, Debra; Ruiz, Maria Elena; Abbott, Stephen

 Department of Infectious Diseases, Children’s National Hospital, Washington, District of Columbia, USA; School of Medicine and Health Sciences, George Washington University, Washington, District of Columbia, USA 
 School of Medicine, Case Western Reserve University, Cleveland, Ohio, USA; University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA; Pediatric Infectious Diseases, Rainbow Babies and Children’s Hospital, Cleveland, Ohio, USA 
 Milken Institute School of Public Health, George Washington University, Washington, District of Columbia, USA; Westat, Rockville, Maryland, USA 
 Milken Institute School of Public Health, George Washington University, Washington, District of Columbia, USA 
 Department of Infectious Diseases, Children’s National Hospital, Washington, District of Columbia, USA; School of Medicine and Health Sciences, George Washington University, Washington, District of Columbia, USA; Elizabeth Glaser Pediatric AIDS Foundation, Washington, District of Columbia, USA 
Publication year
2021
Publication date
Jul 2021
Publisher
Oxford University Press
e-ISSN
23288957
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
3170947585
Copyright
© The Author(s) 2021. Published by Oxford University Press on behalf of Infectious Diseases Society of America. This work is published under http://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.