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Abstract
We evaluated stool enteropathogen detection by semiquantitative polymerase chain reaction (PCR) in 108 subjects with travelers’ diarrhea before and 3 weeks after treatment. Stool samples from 21 subjects were positive for the same pathogen species at both visits. We discuss factors that should be considered when interpreting stool PCR data after treatment.
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1 Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Rockville, Maryland; Henry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland; Division of Infectious Diseases, Naval Medical Center, Portsmouth, Virginia
2 Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Rockville, Maryland
3 Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Rockville, Maryland; Henry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland
4 Academic Department of Military Medicine, Royal Centre for Defence Medicine, Birmingham, UK
5 United States Army Medical Research Unit Kenya, Kericho, Kenya
6 Joint Task Force Bravo, Soto Cano Air Base, Comayagua, Honduras
7 Naval Medical Research Center, Silver Spring, Maryland
8 Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand
9 United States Army Medical Research Unit No. 3, Cairo, Egypt
10 University of Virginia, Charlottesville, Virginia
11 F. Edward Hébert School of Medicine, Uniformed Services University, Bethesda, Maryland