Abstract

We evaluated stool enteropathogen detection by semiquantitative polymerase chain reaction (PCR) in 108 subjects with travelers’ diarrhea before and 3 weeks after treatment. Stool samples from 21 subjects were positive for the same pathogen species at both visits. We discuss factors that should be considered when interpreting stool PCR data after treatment.

Details

Title
A Comparison of Stool Enteropathogen Detection by Semiquantitative PCR in Adults With Acute Travelers’ Diarrhea Before and 3 Weeks After Successful Antibiotic Treatment
Author
Tisdale, Michele D 1 ; Tribble, David R 2 ; Telu, Kalyani 3 ; Fraser, Jamie A 3 ; Connor, Patrick 4 ; Cliff, Philip 5 ; Odundo, Elizabeth 5 ; Reyes, Faviola 6 ; Simons, Mark P 7 ; Swierczewski, Brett 8 ; Lizewski, Stephen 9 ; Liu, Jie 10 ; Houpt, Eric 10 ; Riddle, Mark S 11 ; Lalani, Tahaniyat 1 

 Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Rockville, Maryland; Henry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland; Division of Infectious Diseases, Naval Medical Center, Portsmouth, Virginia 
 Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Rockville, Maryland 
 Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Rockville, Maryland; Henry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland 
 Academic Department of Military Medicine, Royal Centre for Defence Medicine, Birmingham, UK 
 United States Army Medical Research Unit Kenya, Kericho, Kenya 
 Joint Task Force Bravo, Soto Cano Air Base, Comayagua, Honduras 
 Naval Medical Research Center, Silver Spring, Maryland 
 Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand 
 United States Army Medical Research Unit No. 3, Cairo, Egypt 
10  University of Virginia, Charlottesville, Virginia 
11  F. Edward Hébert School of Medicine, Uniformed Services University, Bethesda, Maryland 
Publication year
2019
Publication date
May 2019
Publisher
Oxford University Press
e-ISSN
23288957
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
3170955390
Copyright
© The Author(s) 2019. Published by Oxford University Press on behalf of Infectious Diseases Society of America. This work is published under http://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.