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Abstract
We report 5 HIV-infected Ugandan adults with cryptococcal and tuberculous (TB) meningitis co-infection. All unmasked meningitis occurred within 5 weeks of starting HIV therapy. Xpert MTB/RIF Ultra facilitated prompt diagnosis; however, 60% in-hospital mortality occurred. TB meningitis coinfection prevalence was 0.8% (5/586) among cryptococcal meningitis, 2 during second cryptococcal episodes.
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Details
1 Infectious Diseases Institute, College of Health Sciences, Makerere University Kampala, Kampala, Uganda; Hospital for Tropical Diseases, University College London Hospitals NHS Foundation Trust, London, United Kingdom
2 Infectious Diseases Institute, College of Health Sciences, Makerere University Kampala, Kampala, Uganda; Clinical Research Department, London School of Hygiene and Tropical Medicine, Keppel Street, London, United Kingdom
3 Infectious Diseases Institute, College of Health Sciences, Makerere University Kampala, Kampala, Uganda; Division of Infectious Diseases and International Medicine, Department of Medicine, University of Minnesota, Minneapolis
4 Infectious Diseases Institute, College of Health Sciences, Makerere University Kampala, Kampala, Uganda
5 Division of Infectious Diseases and International Medicine, Department of Medicine, University of Minnesota, Minneapolis