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Abstract
In a male with severe proctitis, monkeypox virus DNA was detected in skin lesions, blood, the nasopharynx, and the rectum, underlying generalized viral spreading. Rectal involvement was still found when skin lesions disappeared. At this early stage, an increase of cytotoxic and activated T cells was observed, while a reduction in CD56dimCD57+ NK cells compared with recovery time point was observed.
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Details
1 Department of Public Health and Infectious Diseases, Sapienza University of Rome , Rome , Italy
2 Infectious Diseases Unit, SM Goretti Hospital, Sapienza University of Rome , Latina , Italy
3 Department of Molecular Medicine, Sapienza University of Rome , Rome , Italy