Abstract

The ability to correctly understand the emotional expression of another person is essential for social relationships and appears to be a partly inherited trait. The neuropeptides oxytocin and vasopressin have been shown to influence this ability as well as face processing in humans. Here, recognition of the emotional content of faces and voices, separately and combined, was investigated in 492 subjects, genotyped for 25 single nucleotide polymorphisms (SNPs) in eight genes encoding proteins important for oxytocin and vasopressin neurotransmission. The SNP rs4778599 in the gene encoding aryl hydrocarbon receptor nuclear translocator 2 (ARNT2), a transcription factor that participates in the development of hypothalamic oxytocin and vasopressin neurons, showed an association that survived correction for multiple testing with emotion recognition of audio–visual stimuli in women (n = 309). This study demonstrates evidence for an association that further expands previous findings of oxytocin and vasopressin involvement in emotion recognition.

Details

Title
Emotion recognition associated with polymorphism in oxytocinergic pathway gene ARNT2
Author
Hovey, Daniel 1 ; Henningsson, Susanne 1 ; Cortes, Diana S 2 ; Bänziger, Tanja 3 ; Zettergren, Anna 4 ; Melke, Jonas 1 ; Fischer, Håkan 2 ; Laukka, Petri 2 ; Westberg, Lars 1 

 Department of Pharmacology, Institute of Neuroscience and Physiology at the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden 
 Department of Psychology, Stockholm University, Stockholm, Sweden 
 Department of Psychology, Mid Sweden University, Östersund, Sweden 
 Department of Pharmacology, Institute of Neuroscience and Physiology at the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology at the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden 
Pages
173-181
Publication year
2018
Publication date
Feb 2018
Publisher
Oxford University Press
ISSN
17495016
e-ISSN
17495024
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
3171534638
Copyright
© The Author(s) (2017). Published by Oxford University Press. This work is published under http://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.