A comparative study of peak expiratory flow rate between midozolam induced and propofol induced post anesthetic patients in recovery phase conducted at Government Hospital Chittoor- a district of South India

Abstract

PEFR values can reflect large airway flow which depends on various factors in healthy individuals suchas gender, intra and extra thoracic diameters, ability of alveolar expansion, elastic recoiling ability of the lungs, voluntary efforts, and strength of the respiratory muscles. [...]PEFR values of the patients preoperative and postoperatively will reflect the effect of general anesthesia on lungs and respiration. A deeper level of anesthesia can lead to a significant decrease in the functional residual capacity and increased lung clearance index, an index for ventilation distribution (von Ungern-Sternberg et al, 2007). There are no significant studies to show the comparison between Midazolam and Propofol induction effect on respiratory depression which can indirectly point to respiratory strength regain during post-anesthetic recovery period. Because both Midazolam and propofol are the most commonly used induction drugs-we aimed: after the results, will be able to suggest their appropriate application in induction for patients with pre-existing respiratory illnesses. [...]the results of the current study, i.e., midazolam depresses the respiratory system more than that of propofol can be attributed to one of their mentioned causes.