1. Introduction
Air pollution is the leading environmental risk factor for human health [1], significantly contributing to increased morbidity and mortality, particularly in urban areas. In 2021, air pollution accounted for 8.1 million deaths globally, making it the second most common cause of premature mortality after hypertension [2]. Among air pollutants, coarse particulate matter with an aerodynamic diameter of less than 10 μm (PM10) has been strongly associated with the onset and exacerbation of respiratory and cardiovascular diseases [3,4,5,6,7,8]. These particles, primarily originating from fossil fuel combustion, industrial emissions, urban dust, and agricultural activities, disproportionately affect vulnerable populations such as the elderly and individuals with pre-existing comorbidities [9,10,11,12,13,14,15]. Longitudinal studies have linked elevated PM10 levels to the development of new atherosclerotic lesions and increased risks of myocardial infarction, particularly in individuals with cardiovascular disease or a high body mass index [16,17]. Moreover, recent research demonstrates that reducing PM10 levels correlates with decreased public healthcare costs and fewer hospitalizations for respiratory and cardiovascular diseases [18,19,20,21,22].
Since the establishment of Brazil’s first air quality resolution, CONAMA Resolution No. 03/1990 [23], the country has faced persistent challenges, including vague guidelines, outdated standards compared to the international recommendations, and the absence of concrete deadlines for achieving its interim targets [24]. Even where Brazil updated its air pollutant limit values to align with the World Health Organization (WHO)’s 2005 guidelines through CONAMA Resolution No. 491/2018 [25], the lack of a progressive strategy and well-defined timelines limited its effectiveness [24]. Furthermore, this resolution quickly became outdated following the release of the revised WHO air quality guideline values in 2021 [26].
In a significant policy shift and in response to the growing health impacts of air pollution, Brazil undertook a comprehensive revision of its air quality policy framework. This effort culminated in the enactment of CONAMA Resolution No. 506 on 5 July 2024 [27], which introduced specific deadlines for the interim air quality targets and aligned its ultimate goal with the 2021 WHO guidelines [26]. The resolution established phased targets for 2025, 2033, and 2044, marking a considerable improvement in strategic planning. Additionally, it incorporated innovative measures such as regulating the Air Quality Index and mandating continuous monitoring by state entities, thereby enhancing the transparency and accessibility of air quality data. Despite these advancements, as highlighted by Tavella et al. [24], the extended timelines for achieving these targets and the absence of a defined deadline for the final goal reflect a cautious approach that may fail to address the urgency of reducing air pollution’s health impacts.
The link between air quality and human health is well documented [3,9,28,29,30,31,32,33,34,35,36,37,38], with PM10 pollution emerging as a major contributor to chronic diseases [4,6,7,8,39,40,41,42,43,44,45]. Persistently high PM10 levels not only exacerbate respiratory and cardiovascular conditions but also impose significant economic and social costs. Implementing public policies that prioritize reductions in PM10 is not merely an environmental health initiative but a direct investment in improving quality of life and reducing pressures on the healthcare system. Accelerating efforts to meet the global standards is essential to ensuring cleaner air and healthier communities.
The city of Rio Grande, located in Rio Grande do Sul State, southern Brazil, exemplifies the complexities of addressing air pollution. While its geographic characteristics facilitate pollutant dispersion during certain seasons, its economic characteristics contribute to high particulate matter concentrations, driven by industrial activities such as refineries, food processing, metallurgy, and intense port operations [46]. Notably, this city’s lack of a clear distinction between industrial and urban zones, with industrial areas often being adjacent to or overlapping with residential neighborhoods, intensifies human exposure to air pollution. For reasons shaped by these and other factors, the city is the subject of ongoing investigations into air pollution and its impacts, further highlighting its relevance for understanding and addressing these challenges [47,48,49,50,51]. Furthermore, the city’s aging population exacerbates the health impacts of air pollution [52]. Additionally, a recent study conducted in the metropolitan region of Rio Grande do Sul, spanning two decades of data (2002–2021), demonstrated the significant health impacts of air pollution on the local population, underscoring the urgency of mitigating air quality issues in this state [53].
In light of the above, our study sought to analyze the economic and public health benefits of accelerating the PM10 reduction targets in Rio Grande, focusing on reducing the healthcare costs associated with hospitalizations for respiratory and cardiovascular diseases and estimating the decrease in non-external mortality attributable to air pollution. The central hypothesis is that advancing these targets would generate significant healthcare savings while reducing mortality. By analyzing the hospitalization data and atmospheric PM10 concentrations in Rio Grande, this study seeks to provide robust evidence supporting the need to expedite the targets outlined in CONAMA’s resolution [27]. These findings contribute to the international discourse on the intersection of environmental regulation and public health, emphasizing the economic and health benefits of more ambitious air quality policies.
2. Materials and Methods
2.1. The Study Area
The city of Rio Grande (32°01′40″ S; 52°05′40″ W), located in the state of Rio Grande do Sul, Brazil (Figure 1), spans an area of approximately 2683 km2 and has a population of around 191 thousand inhabitants [54]. The local economy relies heavily on a large industrial complex, including industries such as fertilizers, petroleum, food processing, fishery, and metallurgy, as well as intense port activities. The port of Rio Grande is the fifth busiest in Brazil [55]. In this city, industrial and urban zones are closely intertwined, with residential areas often being situated near industrial activities, which increases the potential for human exposure to air pollutants. This region features a subtropical climate characterized by moderate humidity, cold winters, mild summers, and abundant rainfall distributed throughout the year [56].
2.2. The Sampling Procedure and Monitoring Period
PM10 concentration data were collected by the company Catavento Meteorologia at three sampling sites located within the influence area of the TECON Rio Grande container terminal, as illustrated in Figure 1. The georeferenced locations were as follows: Site 1 (32°7′49.27″ S, 52°6′11.72″ W), Site 2 (32°7′34.19″ S, 52°6′39.57″ W), and Site 3 (32°7′21.08″ S, 52°6′12.82″ W). The primary sources of pollutants in this area included industrial emissions and emissions from truck and heavy vehicle exhausts during container-loading and -unloading activities. These sites are adjacent to urban neighborhoods, where residential areas are directly influenced by industrial and urban emissions, capturing pollution from a diverse range of sources. This proximity to both industrial and residential zones ensures the representativeness of the collected data, making these sampling locations well suited to assessing the combined health impacts of urban and industrial air pollution in Rio Grande. Furthermore, the sampling sites were selected based on the pollutant source types, the prevailing wind direction in the region, and the availability of infrastructure for air quality monitoring stations.
PM10 monitoring was conducted following the methodology outlined in the NBR 13.412 standard of the Brazilian Association of Technical Standards (ABNT), using active air sampling procedures and equipment [57]. The method employed high-volume samplers equipped with inertial separators calibrated to retain particles with an aerodynamic diameter ≤10 µm. Each sampling point was operated for 24 consecutive hours, with the air flows controlled between 1.02 and 1.24 m3/min, ensuring representative collection even under dynamic meteorological conditions. The particulate matter was deposited onto pre-conditioned fiberglass filters stabilized in the laboratory for gravimetric control. After collection, the filters were subjected to precise analytical weighing before and after exposure to determine the mass of the retained particles. The concentration was calculated as the ratio between the mass collected and the total volume of air sampled. The evaluation period spanned from January 2017 to November 2019. Data were provided by Catavento Meteorologia in the form of air quality reports, with each containing the 24 h average PM10 concentrations for the three monitoring sites.
2.3. Health Data Acquisition
Health-related data, including total population, the number of hospitalizations due to cardiac diseases (I00-I52) across all age groups, and respiratory diseases (J00-J99) segmented by age groups (all ages, 15–64 years, and 65 years or older), as well as the average cost of hospitalizations, were obtained from the database of the Unified Health System’s Informatics Department (DATASUS) [58].
2.4. The Health Impact Assessment
The health impact assessment (HIA) was performed using the “tool short term” spreadsheet (rev. Sept 2013) developed by the APHEKOM project (Improving Knowledge and Communication for Decision Making on Air Pollution and Health in Europe). This tool provides insights and methodologies to assist policymakers in implementing more effective air quality strategies [59]. Despite being widely used in Europe, this methodology has also been applied in Brazil, including studies conducted in cities within the state of Rio Grande do Sul [52] and major Brazilian capital cities [53,60,61,62,63], demonstrating its applicability in the Brazilian context. In this study, the spreadsheet was customized using local data specific to Rio Grande, ensuring the methodology aligned with the city’s individual characteristics.
Three scenarios were simulated to assess their health benefits, corresponding to annual PM10 concentrations set at the new limits proposed by CONAMA Resolution No. 506/2024: 30 µg/m3, 20 µg/m3, and 15 µg/m3. The health benefits associated with reduced PM10 levels (short-term exposure) were calculated using Equation (1):
(1)
where Δy represents the health benefits associated with PM10 reduction (the annual reduction in deaths or hospitalizations), y0 is the initial number of deaths or hospitalizations, β is the coefficient for the concentration–response function, and Δx is the reduction in the pollutant concentration for a specific scenario (µg/m3). The resulting Δy values were rounded to the nearest whole number to represent complete cases.2.5. The Economic Cost Assessment
The economic assessment of the hospitalization costs due to respiratory and cardiac diseases was conducted based on the average daily cost and the mean length of hospital stays [60]. These data, derived from DATASUS, represented the average values for 2017, 2018, and 2019. The APHEKOM spreadsheet was also employed for this assessment, using the following, Equation (2):
(2)
where Ch is the total hospitalization cost, Vi is the daily hospitalization cost for cardiac or respiratory diseases, Nd is the average length of stay (days) for cardiac or respiratory hospitalizations, and Nc is the number of cases for cardiac or respiratory diseases attributed to PM10. While Vi and Nd are obtained from DATASUS data, the number of cases due to a certain disease attributable to PM10 can be found in Table 1 and Table 2 in Section 3.2.6. Mortality Attributable to Air Pollution
The estimation of deaths attributed to PM10 exposure (non-external total mortality) was conducted using the methodology proposed by Ostro et al. [64]. The average PM10 concentration for 2017–2019 and the concentrations of 30 µg/m3, 20 µg/m3, and 15 µg/m3 proposed by CONAMA Resolution No. 506/2024 were used. The following, Equations (3) and (4), were applied:
(3)
(4)
where RR is the relative risk, X is the annual average PM10 concentration, X0 is the concentration proposed by CONAMA, β is the concentration–response coefficient, Nattributable is the number of deaths attributed to PM10, and Ntotal is the total number of deaths. A concentration–response coefficient (β) of 0.0008 was chosen based on the best estimate proposed by Ostro et al. [30] for regions without specific studies on this relationship in the population. The resulting Nattributable values were rounded to the nearest whole number to represent complete cases.3. Results and Discussion
CONAMA Resolution No. 506/2024 establishes national air quality standards for PM10, measured as the annual arithmetic mean of the pollutant concentration in micrograms per cubic meter (µg/m3) under conditions of 25 °C and an atmospheric pressure of 760 mmHg. The resolution outlines a five-phase timeline for implementing these standards. The first phase retains the current limit of 40 µg/m3 until 31 December 2024. The second phase sets the limit at 35 µg/m3, to be achieved by January 2025. The third phase lowers the limit to 30 µg/m3 by 2033, while the fourth phase reduces it further to 20 µg/m3 by January 2044, with an optional adjustment to 2040 or 2048. Finally, the fifth phase establishes a guideline value of 15 µg/m3, recommended by the WHO in 2021, but does not specify a target year for its implementation. For analysis purposes, this study assumed that the 15 µg/m3 limit would be reached by 2055, maintaining the 11-year interval proposed between phases 3 and 4.
First of all, the PM10 concentration found in our study for 2017–2019 averaged 50.0 µg/m3 across the three sampling sites. The site-specific concentrations were 52.6 µg/m3 at Site 1, 49.9 µg/m3 at Site 2, and 47.5 µg/m3 at Site 3. These values were sufficiently similar to justify the use of an average, as no significant site-specific variations were observed in the evaluated region. Based on this average concentration, all of the results could be further calculated. Table 1 presents the number of avoidable respiratory and cardiac hospitalizations and the associated cost savings if the PM10 concentration levels proposed by CONAMA for phases 3, 4, and 5 were reached in 2025. It is important to note that phases 1 and 2 are already in effect, making it unnecessary to evaluate the impacts of advancing these phases individually. However, their potential benefits are incorporated into the current evaluation of the subsequent phases, as the average PM10 concentration in the city exceeds the limits established for these earlier phases. The findings demonstrate that lower pollutant concentrations result in a greater number of avoidable hospitalizations and consequently higher economic savings. Respiratory diseases exhibited a higher sensitivity to PM10 reductions, as indicated by the greater number of preventable hospitalizations. However, the cost savings from respiratory and cardiac hospitalizations were similar, primarily due to the difference in the average hospitalization costs: BRL 2282.79 for cardiac cases and BRL 1478.96 for respiratory cases, according to DATASUS.
Table 1The number of avoided cases and cost savings associated with respiratory and cardiac hospitalizations if the interim targets for PM10 were advanced.
Respiratory Hospitalizations | Cardiac Hospitalization | |||||
---|---|---|---|---|---|---|
Scenario | Original Year | Years Advanced | Avoided | Savings (BRL) | Avoided | Savings (BRL) |
30 µg/m3 | 2033 | 8 | 395 | 583,301.82 | 238 | 542,390.90 |
20 µg/m3 | 2044 | 19 | 1398 | 2,068,177.66 | 844 | 1,925,761.64 |
15 µg/m3 | 2055 | 30 | 2568 | 3,797,969.28 | 1551 | 3,540,607.29 |
Number of avoided non-external deaths associated with advancing the interim targets for the PM10 concentration.
Scenario | Original Year | Years Advanced | Annual Non-External Deaths Avoided | Total Non-External Deaths Avoided |
---|---|---|---|---|
30 µg/m3 | 2033 | 8 | 22 | 173 |
20 µg/m3 | 2044 | 19 | 32 | 614 |
15 µg/m3 | 2055 | 30 | 38 | 1128 |
Critically, though superficially, extrapolating the findings from Rio Grande, a city with approximately 200,000 inhabitants and average PM10 concentrations of approximately 50 µg/m3, to broader urban and industrial centers provides valuable information on the potential benefits of advancing the PM10 reduction targets. To illustrate this, we provide a brief analysis of Porto Alegre, the capital of Rio Grande do Sul, with a population exceeding 1.3 million and a similar meteorological context. In this scenario, considering the same average concentration of PM10 as that in Rio Grande, achieving the WHO’s guideline of 15 µg/m3 could prevent over 27,000 hospitalizations due to respiratory and cardiac diseases; save more than BRL 24.7 million in respiratory-related hospitalization costs and BRL 23 million in cardiac-related hospitalization costs; and avoid over 7000 non-external deaths. However, it is important to emphasize that the sources of emissions in Porto Alegre differ significantly from those in Rio Grande. This extrapolation is not meant to represent the actual conditions in Porto Alegre but rather to provide a hypothetical illustration of the potential benefits of advancing these targets if the pollutant levels were similar.
While these extrapolations provide a broader perspective, estimates for other localities or for the entire country are challenging to conduct at this stage due to Brazil’s highly heterogeneous pollution levels and the sparse coverage of its air quality monitoring network, which currently covers only 1.6% of its municipalities [65]. Additionally, a recent report by the Brazilian Institute of Energy and Environment revealed that only 11 of Brazil’s 27 state capitals (including the national capital Brasilia) have any form of air quality monitoring [66], further underscoring the critical gaps in data availability. This highlights the need for more robust monitoring systems and localized analyses to refine the projections.
Nonetheless, focusing on densely populated, heavily industrialized cities or cities with recognized high emissions based on other factors, where the pollutant levels may match or exceed those observed in Rio Grande, underscores the urgency of advancing the PM10 targets. These regional analyses not only strengthen the argument for policy interventions but also provide more tailored approaches to guiding decision-making, emphasizing the profound benefits of improving air quality in the Brazilian context.
Air pollution in the south of Brazil has characteristics influenced by a combination of natural and anthropogenic emissions. Studies conducted in this region have shown that the particulate matter concentrations often exceed the standards recommended by the WHO and CONAMA. High levels of particulate matter have been linked to emissions from vehicular traffic, industrial activities, and urban sources, alongside the role of local meteorological conditions, such as wind speed, which can either disperse or intensify pollution levels [47,50,51,53,67].
While the potential benefits of advancing the PM10 reduction targets are evident, significant barriers must be overcome for their successful implementation. Economic barriers, such as the high costs associated with transitioning to cleaner industrial processes and transportation systems, may hinder progress, particularly in regions with limited financial resources. Politically, competing priorities and resistance from stakeholders affected by stricter regulations can delay or weaken policy adoption. Logistically, the limited capacity of Brazil’s air quality monitoring network and the complexity of enforcing compliance across diverse regions present further obstacles. Overcoming these barriers requires coordinated efforts among policymakers, industry, and civil society, alongside substantial investments in monitoring infrastructure, technological innovation, and public engagement, to ensure the successful implementation of accelerated air quality improvements. Nevertheless, even advancing these targets by a few years rather than waiting the 30 years outlined in current timelines would represent a significant victory for public health and a major step forward for sustainable development in Brazil.
To the best of our knowledge, this is the first study to evaluate the economic and health impacts of advancing the targets proposed by CONAMA Resolution No. 506/2024. Its results underscore the substantial benefits of accelerating air quality improvements in industrial and urbanized cities similar to Rio Grande. The novelty of this approach lies in its ability to translate recent regulatory decisions into tangible health and economic benefits, making a compelling case for policymakers. We highlight that future studies should adopt a similar approach to guiding policy adjustments, not only considering the WHO’s guideline value as a fixed reference but also evaluating intermediate targets that are more feasible for low- and middle-income countries, where achieving the strictest standards in the short term may present significant challenges.
However, this study is subject to limitations. First, it relies on modeled scenarios that assume uniform pollutant reductions, which may not reflect localized variations in the pollution sources and meteorological conditions. Second, the analysis does not account for indirect economic benefits, such as productivity gains due to improved public health, potentially underestimating the total economic impact. Finally, the limited spatial coverage of air quality monitoring in Brazil poses challenges in applying this methodology, emphasizing the need for amore robust air quality monitoring network to improve the data acquisition and support future studies. Expanding air quality monitoring systems is critical to strengthening the foundation of informed decision-making and effective policy implementation.
In addition, applying similar methodologies to other localities requires consideration of specific contextual factors. For instance, the hospitalization data from DATASUS, while comprehensive, may have inherent limitations. Regional disparities in healthcare access could influence hospitalization rates, with under-resourced areas potentially underreporting cases due to limited healthcare access rather than lower pollution exposure. Moreover, the data may not fully account for confounding factors unrelated to PM₁₀ exposure, such as pre-existing health conditions or other environmental stressors. Similarly, the concentration–response coefficient used in this study is based on global estimates for regions without specific studies, which may not fully capture the unique health responses of the population in Rio Grande. This underscores the importance of future research to develop localized concentration–response functions that reflect the demographic, environmental, and health characteristics of the city better. Future studies should also explore the incorporation of real-time air quality monitoring data and broader spatial coverage to build on these findings.
4. Conclusions
Advancing the targets for reducing the PM10 levels to 15 µg/m3 by 2025, instead of 2055, would prevent 2568 respiratory hospitalizations, 1551 cardiac hospitalizations, and 1128 deaths attributable to air pollution, resulting in a cost saving of BRL 7.3 million for the healthcare system in the city of Rio Grande alone. At the national level, these benefits become even more substantial. Although CONAMA Resolution No. 506/2024 represents progress by introducing specific interim targets, the lack of a definitive deadline for achieving the final guideline value of 15 µg/m3 limits the resolution’s overall effectiveness. The findings of this study underscore the critical need for more ambitious policies aligned with the 2021 WHO recommendations, demonstrating that accelerating air quality targets not only reduces economic costs but also significantly improves public health outcomes and life expectancy. Furthermore, expanding the air quality monitoring coverage and incorporating real-time data collection are essential to enhancing the robustness of public policies and ensuring transparency. Currently, only a fraction of Brazilian municipalities benefit from adequate air quality monitoring, leaving critical gaps in the data that hinder an accurate assessment of pollution’s health impacts and the efficacy of mitigation measures. Strengthening these systems, combined with broader regional analyses, will allow policymakers to address the diverse sources and consequences of air pollution across Brazil better. This study highlights the importance of integrated environmental strategies that prioritize both public health and economic sustainability. By advancing these efforts, Brazil can more effectively mitigate the health and economic burdens of air pollution while ensuring a healthier and more sustainable future for its population.
Conceptualization: L.H.A.L.e.M., Y.F.C.L., A.d.S.B., R.A.T. and F.M.R.d.S.J. Methodology: L.H.A.L.e.M., Y.F.C.L., G.d.O.S., N.P. and F.M.R.d.S.J. Software: L.H.A.L.e.M., Y.F.C.L., G.d.O.S. and F.M.R.d.S.J. Validation: L.H.A.L.e.M., Y.F.C.L., G.d.O.S., R.A.T., A.d.S.B., R.d.L.B. and N.P. Formal analysis: L.H.A.L.e.M., Y.F.C.L., G.d.O.S., N.P. and F.M.R.d.S.J. Investigation: L.H.A.L.e.M., Y.F.C.L., A.d.S.B., R.A.T. and F.M.R.d.S.J. Resources: N.P. and F.M.R.d.S.J. Data curation: L.H.A.L.e.M., Y.F.C.L., A.d.S.B., R.A.T., R.d.L.B. and F.M.R.d.S.J. Writing—original draft preparation: L.H.A.L.e.M., Y.F.C.L., A.d.S.B., R.A.T. and F.M.R.d.S.J. Writing—review and editing: R.A.T. and F.M.R.d.S.J. Visualization: L.H.A.L.e.M., Y.F.C.L., G.d.O.S., R.A.T., A.d.S.B., R.d.L.B. and F.M.R.d.S.J. Supervision: F.M.R.d.S.J. Project administration: F.M.R.d.S.J. Funding acquisition: F.M.R.d.S.J. All authors have read and agreed to the published version of the manuscript.
Not applicable.
Not applicable.
The health data presented in this study are available in the DATASUS Tabnet system, under reference number 58. The raw data on air pollution supporting the conclusions of this article can be made available by the authors on request.
The authors thank the Catavento Meteorologia e Meio Ambiente and Universidade Federal do Rio Grande, FURG, for making the data available and providing logistical support for carrying out the research.
The authors declare no conflicts of interest.
The following abbreviations are used in this manuscript:
PM10 | Coarse particulate matter with an aerodynamic diameter of less than 10 μm |
CONAMA | National Environment Council |
WHO | World Health Organization |
Footnotes
Disclaimer/Publisher’s Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content.
Figure 1. Geographic location of Rio Grande, southern Brazil, highlighting the PM₁₀ sampling sites (red dots) in the city.
References
1. Brauer, M.; A Roth, G.; Aravkin, A.Y.; Zheng, P.; Abate, K.H.; Abate, Y.H.; Abbafati, C.; Abbasgholizadeh, R.; Abbasi, M.A.; Abbasian, M. et al. Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: A systematic analysis for the Global Burden of Disease Study 2021. Lancet; 2024; 403, pp. 2162-2203. [DOI: https://dx.doi.org/10.1016/s0140-6736(24)00933-4]
2. Health Effects Institute. State of Global Air 2024. Special Report; Health Effects Institute: Boston, MA, USA, 2024; Available online: https://www.stateofglobalair.org/resources/report/state-global-air-report-2024 (accessed on 26 December 2024).
3. Manisalidis, I.; Stavropoulou, E.; Stavropoulos, A.; Bezirtzoglou, E. Environmental and Health Impacts of Air Pollution: A Review. Front. Public Health; 2020; 8, 14. [DOI: https://dx.doi.org/10.3389/fpubh.2020.00014]
4. Feng, W.; Li, H.; Wang, S.; Van Halm-Lutterodt, N.; An, J.; Liu, Y.; Liu, M.; Wang, X.; Guo, X. Short-term PM10 and emergency department admissions for selective cardiovascular and respiratory diseases in Beijing, China. Sci. Total Environ.; 2019; 657, pp. 213-221. [DOI: https://dx.doi.org/10.1016/j.scitotenv.2018.12.066] [PubMed: https://www.ncbi.nlm.nih.gov/pubmed/30543969]
5. Bălă, G.-P.; Râjnoveanu, R.-M.; Tudorache, E.; Motișan, R.; Oancea, C. Air pollution exposure—The (in)visible risk factor for respiratory diseases. Environ. Sci. Pollut. Res.; 2021; 28, pp. 19615-19628. [DOI: https://dx.doi.org/10.1007/s11356-021-13208-x]
6. Tahery, N.; Geravandi, S.; Goudarzi, G.; Shahriyari, H.A.; Jalali, S.; Mohammadi, M.J. Estimation of PM10 pollutant and its effect on total mortality (TM), hospitalizations due to cardiovascular diseases (HACD), and respiratory disease (HARD) outcome. Environ. Sci. Pollut. Res.; 2021; 28, pp. 22123-22130. [DOI: https://dx.doi.org/10.1007/s11356-020-12052-9]
7. Liu, S.; Wang, L.; Zhou, L.; Li, W.; Pu, X.; Jiang, J.; Chen, Y.; Zhang, L.; Qiu, H. Differential effects of fine and coarse particulate matter on hospitalizations for ischemic heart disease: A population-based time-series analysis in Southwestern China. Atmos. Environ.; 2020; 224, 117366. [DOI: https://dx.doi.org/10.1016/j.atmosenv.2020.117366]
8. Chen, R.; Yin, P.; Meng, X.; Wang, L.; Liu, C.; Niu, Y.; Liu, Y.; Liu, J.; Qi, J.; You, J. et al. Associations between coarse particulate matter air pollution and cause-specific mortality: A nationwide analysis in 272 Chinese cities. Environ. Health Perspect.; 2019; 127, 17008. [DOI: https://dx.doi.org/10.1289/ehp2711] [PubMed: https://www.ncbi.nlm.nih.gov/pubmed/30702928]
9. Tran, H.M.; Tsai, F.-J.; Lee, Y.-L.; Chang, J.-H.; Chang, L.-T.; Chang, T.-Y.; Chung, K.F.; Kuo, H.-P.; Lee, K.-Y.; Chuang, K.-J. et al. The impact of air pollution on respiratory diseases in an era of climate change: A review of the current evidence. Sci. Total. Environ.; 2023; 898, 166340. [DOI: https://dx.doi.org/10.1016/j.scitotenv.2023.166340] [PubMed: https://www.ncbi.nlm.nih.gov/pubmed/37591374]
10. Jin, T.; Di, Q.; Réquia, W.J.; Yazdi, M.D.; Castro, E.; Ma, T.; Wang, Y.; Zhang, H.; Shi, L.; Schwartz, J. Associations between long-term air pollution exposure and the incidence of cardiovascular diseases among American older adults. Environ. Int.; 2022; 170, 107594. [DOI: https://dx.doi.org/10.1016/j.envint.2022.107594]
11. Renzi, M.; Badaloni, C.; Trentalange, A.; Porta, D.; Davoli, M.; Michelozzi, P. Association between air pollution, socioeconomic inequalities and cause specific mortality in a large administrative cohort in a contaminated site of central Italy. Atmos. Environ.; 2025; 347, 121082. [DOI: https://dx.doi.org/10.1016/j.atmosenv.2025.121082]
12. Jbaily, A.; Zhou, X.; Liu, J.; Lee, T.-H.; Kamareddine, L.; Verguet, S.; Dominici, F. Air pollution exposure disparities across US population and income groups. Nature; 2022; 601, pp. 228-233. [DOI: https://dx.doi.org/10.1038/s41586-021-04190-y]
13. Rentschler, J.; Leonova, N. Global air pollution exposure and poverty. Nat. Commun.; 2023; 14, 4432. [DOI: https://dx.doi.org/10.1038/s41467-023-39797-4]
14. Fairburn, J.; Schüle, S.A.; Dreger, S.; Hilz, L.K.; Bolte, G. Social inequalities in exposure to ambient air pollution: A systematic review in the WHO european region. Int. J. Environ. Res. Public Health; 2019; 16, 3127. [DOI: https://dx.doi.org/10.3390/ijerph16173127] [PubMed: https://www.ncbi.nlm.nih.gov/pubmed/31466272]
15. Maung, T.Z.; Bishop, J.E.; Holt, E.; Turner, A.M.; Pfrang, C. Indoor air pollution and the health of vulnerable groups: A systematic review focused on particulate matter (PM), volatile organic compounds (VOCs) and their effects on children and people with pre-existing lung disease. Int. J. Environ. Res. Public Health; 2022; 19, 8752. [DOI: https://dx.doi.org/10.3390/ijerph19148752]
16. Wu, K.; Ho, H.C.; Su, H.; Huang, C.; Zheng, H.; Zhang, W.; Tao, J.; Hossain, M.Z.; Zhang, Y.; Hu, K. et al. A systematic review and meta-analysis of intraday effects of ambient air pollution and temperature on cardiorespiratory morbidities: First few hours of exposure matters to life. EBioMedicine; 2022; 86, 104327. [DOI: https://dx.doi.org/10.1016/j.ebiom.2022.104327] [PubMed: https://www.ncbi.nlm.nih.gov/pubmed/36323182]
17. Urbanowicz, T.; Skotak, K.; Olasińska-Wiśniewska, A.; Filipiak, K.J.; Bratkowski, J.; Wyrwa, M.; Sikora, J.; Tyburski, P.; Krasińska, B.; Krasiński, Z. et al. Long-Term Exposure to PM10 Air Pollution Exaggerates Progression of Coronary Artery Disease. Atmosphere; 2024; 15, 216. [DOI: https://dx.doi.org/10.3390/atmos15020216]
18. Wang, S.; Song, R.; Xu, Z.; Chen, M.; Di Tanna, G.L.; Downey, L.; Jan, S.; Si, L. The costs, health and economic impact of air pollution control strategies: A systematic review. Glob. Health Res. Policy; 2024; 9, 30. [DOI: https://dx.doi.org/10.1186/s41256-024-00373-y] [PubMed: https://www.ncbi.nlm.nih.gov/pubmed/39164785]
19. Ye, T.; Guo, S.; Xie, Y.; Chen, Z.; Abramson, M.J.; Heyworth, J.; Hales, S.; Woodward, A.; Bell, M.; Guo, Y. et al. Health and related economic benefits associated with reduction in air pollution during COVID-19 outbreak in 367 cities in China. Ecotoxicol. Environ. Saf.; 2021; 222, 112481. [DOI: https://dx.doi.org/10.1016/j.ecoenv.2021.112481]
20. Castro, A.; Künzli, N.; Götschi, T. Health benefits of a reduction of PM10 and NO2 exposure after implementing a clean air plan in the Agglomeration Lausanne-Morges. Int. J. Hyg. Environ. Health; 2017; 220, pp. 829-839. [DOI: https://dx.doi.org/10.1016/j.ijheh.2017.03.012] [PubMed: https://www.ncbi.nlm.nih.gov/pubmed/28411064]
21. Mebrahtu, T.F.; Santorelli, G.; Yang, T.C.; Wright, J.; Tate, J.; McEachan, R.R. The effects of exposure to NO2, PM2.5 and PM10 on health service attendances with respiratory illnesses: A time-series analysis. Environ. Pollut.; 2023; 333, 122123. [DOI: https://dx.doi.org/10.1016/j.envpol.2023.122123] [PubMed: https://www.ncbi.nlm.nih.gov/pubmed/37390911]
22. Khoshnevis Yazdi, S.; Khanalizadeh, B. Air pollution, economic growth and health care expenditure. Econ. Res.-Ekon. Istraž.; 2017; 30, pp. 1181-1190. [DOI: https://dx.doi.org/10.1080/1331677x.2017.1314823]
23. National Environment Council (CONAMA), Ministry of Environment and Climate Change, Brazil. CONAMA Resolution no 3, of June 28, 1990. Provides for Air Quality Standards, as Stipulated in PRONAR. 1990; Available online: https://conama.mma.gov.br/?option=com_sisconama&task=arquivo.download&id=100 (accessed on 26 December 2024).
24. Tavella, R.A.; de Moura, F.R.; Miraglia, S.G.E.K.; da Silva Júnior, F.M.R. A New Dawn for Air Quality in Brazil. Lancet Planet. Health; 2024; 8, pp. e717-e718. [DOI: https://dx.doi.org/10.1016/s2542-5196(24)00203-1]
25. National Environment Council (CONAMA), Ministry of Environment and Climate Change, Brazil. CONAMA Resolution N. 491, of November 19, 2018. Provides for Air Quality Standards. 2018; Available online: https://conama.mma.gov.br/?option=com_sisconama&task=arquivo.download&id=766 (accessed on 26 December 2024).
26. World Health Organization (WHO). WHO Global Air Quality Guidelines: Particulate matter (PM2.5 and PM10), Ozone, Nitrogen Dioxide, Sulfur Dioxide and Carbon Monoxide. World Health Organization. 2021; Available online: https://www.who.int/publications/i/item/9789240034228 (accessed on 26 December 2024).
27. National Environment Council (CONAMA), Ministry of Environment and Climate Change, Brazil. CONAMA Resolution No 506, of July 5, 2024. Establishes National Air Quality Standards and Provides Guidelines for Their Application. 2024; Available online: https://conama.mma.gov.br/?option=com_sisconama&task=arquivo.download&id=827 (accessed on 26 December 2024).
28. Tavella, R.A.; Penteado, J.O.; de Lima Brum, R.; da Silva Bonifácio, A.d.S.; Martin, M.C.S.; Saes-Silva, E.; Brum, A.N.; Buffarini, R.; Filho, W.L.F.C.; Adamatti, D.F. et al. An exploratory study on the association between air pollution and health problems (ICD-10) with an emphasis on respiratory diseases. Atmos. Pollut. Res.; 2024; 16, 102377. [DOI: https://dx.doi.org/10.1016/j.apr.2024.102377]
29. Dominski, F.H.; Lorenzetti Branco, J.H.; Buonanno, G.; Stabile, L.; Gameiro da Silva, M.; Andrade, A. Effects of air pollution on health: A mapping review of systematic reviews and meta-analyses. Environ. Res.; 2021; 201, 111487. [DOI: https://dx.doi.org/10.1016/j.envres.2021.111487]
30. Almetwally, A.A.; Bin-Jumah, M.; Allam, A.A. Ambient air pollution and its influence on human health and welfare: An overview. Environ. Sci. Pollut. Res.; 2020; 27, pp. 24815-24830. [DOI: https://dx.doi.org/10.1007/s11356-020-09042-2]
31. Saleh, S.; Shepherd, W.; Jewell, C.; Lam, N.L.; Balmes, J.; Bates, M.N.; Lai, P.S.; Ochieng, C.A.; Chinouya, M.; Mortimer, K. Air pollution interventions and respiratory health: A systematic review. Int. J. Tuberc. Lung Dis.; 2020; 24, pp. 150-164. [DOI: https://dx.doi.org/10.5588/ijtld.19.0417] [PubMed: https://www.ncbi.nlm.nih.gov/pubmed/32127098]
32. Lu, F.; Xu, D.; Cheng, Y.; Dong, S.; Guo, C.; Jiang, X.; Zheng, X. Systematic review and meta-analysis of the adverse health effects of ambient PM2.5 and PM10 pollution in the Chinese population. Environ. Res.; 2015; 136, pp. 196-204. [DOI: https://dx.doi.org/10.1016/j.envres.2014.06.029]
33. Keswani, A.; Akselrod, H.; Anenberg, S.C. Health and clinical impacts of air pollution and linkages with climate change. NEJM Évid.; 2022; 1, EVIDra2200068. [DOI: https://dx.doi.org/10.1056/evidra2200068]
34. Fuller, R.; Landrigan, P.J.; Balakrishnan, K.; Bathan, G.; Bose-O’Reilly, S.; Brauer, M.; Caravanos, J.; Chiles, T.; Cohen, A.; Corra, L. et al. Pollution and health: A progress update. Lancet Planet. Health; 2022; 6, pp. e535-e547. [DOI: https://dx.doi.org/10.1016/s2542-5196(22)00090-0]
35. Sun, Z.; Zhu, D. Exposure to outdoor air pollution and its human health outcomes: A scoping review. PLoS ONE; 2019; 14, e0216550. [DOI: https://dx.doi.org/10.1371/journal.pone.0216550]
36. World Health Organization. Review of Evidence on Health Aspects of Air Pollution: REVIHAAP Project: Technical Report (No. WHO/EURO: 2013-4101-43860-61757). World Health Organization. Regional Office for Europe. 2021; Available online: https://iris.who.int/handle/10665/341712 (accessed on 26 January 2025).
37. Lee, K.K.; Bing, R.; Kiang, J.; Bashir, S.; Spath, N.; Stelzle, D.; Mortimer, K.; Bularga, A.; Doudesis, D.; Joshi, S.S. et al. Adverse health effects associated with household air pollution: A systematic review, meta-analysis, and burden estimation study. Lancet Glob. Health; 2020; 8, pp. e1427-e1434. [DOI: https://dx.doi.org/10.1016/S2214-109X(20)30343-0] [PubMed: https://www.ncbi.nlm.nih.gov/pubmed/33069303]
38. Lee, J.-T. Review of epidemiological studies on air pollution and health effects in children. Clin. Exp. Pediatr.; 2020; 64, 3. [DOI: https://dx.doi.org/10.3345/cep.2019.00843] [PubMed: https://www.ncbi.nlm.nih.gov/pubmed/32517422]
39. Karimi, S.M.; Maziyaki, A.; Moghadam, S.A.; Jafarkhani, M.; Zarei, H.; Moradi-Lakeh, M.; Pouran, H. Continuous exposure to ambient air pollution and chronic diseases: Prevalence, burden, and economic costs. Rev. Environ. Health; 2020; 35, pp. 379-399. [DOI: https://dx.doi.org/10.1515/reveh-2019-0106]
40. Duan, R.; Hao, K.; Yang, T. Air pollution and chronic obstructive pulmonary disease. Chronic Dis. Transl. Med.; 2020; 6, pp. 260-269. [PubMed: https://www.ncbi.nlm.nih.gov/pubmed/33336171]
41. Wu, M.-Y.; Lo, W.-C.; Chao, C.-T.; Wu, M.-S.; Chiang, C.-K. Association between air pollutants and development of chronic kidney disease: A systematic review and meta-analysis. Sci. Total. Environ.; 2020; 706, 135522. [DOI: https://dx.doi.org/10.1016/j.scitotenv.2019.135522] [PubMed: https://www.ncbi.nlm.nih.gov/pubmed/31864998]
42. Arias-Pérez, R.D.; Taborda, N.A.; Gómez, D.M.; Narvaez, J.F.; Porras, J.; Hernandez, J.C. Inflammatory effects of particulate matter air pollution. Environ. Sci. Pollut. Res.; 2020; 27, pp. 42390-42404. [DOI: https://dx.doi.org/10.1007/s11356-020-10574-w]
43. Chen, C.-H.; Wu, C.-D.; Chiang, H.-C.; Chu, D.; Lee, K.-Y.; Lin, W.-Y.; Yeh, J.-I.; Tsai, K.-W.; Guo, Y.-L.L. The effects of fine and coarse particulate matter on lung function among the elderly. Sci. Rep.; 2019; 9, 14790. [DOI: https://dx.doi.org/10.1038/s41598-019-51307-5]
44. Mahapatra, B.; Walia, M.; Avis, W.R.; Saggurti, N. Effect of exposure to PM10 on child health: Evidence based on a large-scale survey from 184 cities in India. BMJ Glob. Health; 2020; 5, e002597. [DOI: https://dx.doi.org/10.1136/bmjgh-2020-002597]
45. Tobias, A.; Karanasiou, A.; Amato, F.; Querol, X. Health effects of desert dust and sand storms: A systematic review and meta-analysis. Environ. Epidemiol.; 2019; 3, 396. [DOI: https://dx.doi.org/10.1097/01.ee9.0000610424.75648.58]
46. Instituto Brasileiro de Geografia e Estatística (IBGE), Brazil. Produto Interno Bruto dos Municípios. 2021; Available online: https://www.ibge.gov.br/estatisticas/economicas/contas-nacionais/9088-produto-interno-bruto-dos-municipios.html (accessed on 26 December 2024).
47. Tavella, R.A.; Brum, R.d.L.; Ramires, P.F.; Santos, J.E.K.; Carvalho, R.B.; Marmett, B.; Vargas, V.M.F.; Baisch, P.R.M.; Júnior, F.M.R. Health impacts of PM2.5-bound metals and PAHs in a medium-sized Brazilian city. Environ. Monit. Assess.; 2022; 194, 622. [DOI: https://dx.doi.org/10.1007/s10661-022-10285-4] [PubMed: https://www.ncbi.nlm.nih.gov/pubmed/35907078]
48. Tavella, R.A.; da Rosa Moraes, N.G.; Aick, C.D.M.; Ramires, P.F.; Pereira, N.; Soares, A.G.; da Silva Júnior, F.M.R. Weekend effect of air pollutants in small and medium-sized cities: The role of policies stringency to COVID-19 containment. Atmos. Pollut. Res.; 2023; 14, 101662. [DOI: https://dx.doi.org/10.1016/j.apr.2023.101662]
49. Tavella, R.A.; da Silva Júnior, F.M.R. Exploring the Interruption-Recovery Pattern of Air Pollutants During the COVID-19 Pandemic in Southern Brazil: An Analysis of the New Normal. MAPAN; 2023; 39, pp. 211-220. [DOI: https://dx.doi.org/10.1007/s12647-023-00681-7]
50. de Lima Brum, R.; Penteado, J.O.; Ramires, P.F.; Tavella, R.A.; Honscha, L.C.; da Silva Freitas, L.; de Moura, F.R.; Bonifácio, A.; da Silva, V.M.; da Silva, L.d. et al. Southern Air Project—Scientific efforts to monitor and measure the impacts of air pollution in southern Brazil. Soc. Impacts; 2024; 4, 100074. [DOI: https://dx.doi.org/10.1016/j.socimp.2024.100074]
51. de Sá, S.S.; Tavella, R.A.; Santos, J.E.K.; Aick, C.D.M.; de Oliveira Silveira, G.; Machado, P.D.W.; Martin, M.C.S.; Ramires, P.F.; Mirlean, N.; Baisch, P.R.M. et al. The Hidden Dangers in the Rain: Human Health Risk Assessment of Fluoride and Nitrate in Rainwater from a Medium-Sized Industrial City. Water Conserv. Sci. Eng.; 2024; 9, 51. [DOI: https://dx.doi.org/10.1007/s41101-024-00284-6]
52. da Silva Bonifácio, A.; de Lima Brum, R.; Tavella, R.A.; They, N.H.; Nadaleti, W.C.; Coronas, M.V.; Saes-Silva, E.; Brum, A.N.; Buffarini, R.; Filho, W.L.F.C. et al. Health impact assessment of air pollutants in simulated temperature scenarios in the largest coal mining region of Brazil. Case Stud. Chem. Environ. Eng.; 2024; 10, 100923. [DOI: https://dx.doi.org/10.1016/j.cscee.2024.100923]
53. Brum, A.N.; de Lima Brum, R.; da Silva Bonifácio, A.; Tavella, R.A.; Penteado, J.O.; Siebel, A.M.; Júnior, F.M.R.d.S.; Zhang, L. Two decades of air pollution: Health impacts in the metropolitan area of Porto Alegre, Brazil. Int. J. Environ. Sci. Technol.; 2025; pp. 1-14. [DOI: https://dx.doi.org/10.1007/s13762-024-06300-5]
54. Instituto Brasileiro de Geografia e Estatística (IBGE), Brazil. Cidades e Estados do País—Rio Grande, Rio Grande do Sul. 2022; Available online: https://cidades.ibge.gov.br/brasil/rs/rio-grande/panorama (accessed on 26 December 2024).
55. Agência Nacional de Transportes Aquaviários (ANTAQ), Brazil. Estatístico Aquaviário. 2024; Available online: https://www.gov.br/antaq/pt-br/central-de-conteudos/publicacoes-da-antaq/estatisticos-aquaviarios (accessed on 26 December 2024).
56. Beck, H.E.; Zimmermann, N.E.; McVicar, T.R.; Vergopolan, N.; Berg, A.; Wood, E.F. Present and future Köppen-Geiger climate classification maps at 1-km resolution. Sci. Data; 2018; 5, 180214. [DOI: https://dx.doi.org/10.1038/sdata.2018.214]
57.
58. Departamento de Informação e Informática do Sistema Único de Saúde (DATASUS). Informações de Saúde—Tabnet. 2024; Available online: https://datasus.saude.gov.br/informacoes-de-saude-tabnet/ (accessed on 26 December 2024).
59. Pascal, M.; Corso, M.; Chanel, O.; Declercq, C.; Badaloni, C.; Cesaroni, G.; Henschel, S.; Meister, K.; Haluza, D.; Martin-Olmedo, P. et al. Assessing the public health impacts of urban air pollution in 25 European cities: Results of the Aphekom project. Sci. Total Environ.; 2013; 449, pp. 390-400. [DOI: https://dx.doi.org/10.1016/j.scitotenv.2013.01.077] [PubMed: https://www.ncbi.nlm.nih.gov/pubmed/23454700]
60. Abe, K.C.; Miraglia, S.G.E.K. Health Impact Assessment of Air Pollution in São Paulo, Brazil. Int. J. Environ. Res. Public Health; 2016; 13, 694. [DOI: https://dx.doi.org/10.3390/ijerph13070694]
61. Rocha, C.A.; Lima, J.L.; Mendonça, K.V.; Marques, E.V.; Zanella, M.E.; Ribeiro, J.P.; Bertoncini, B.V.; Branco, V.T.C.; Cavalcante, R.M. Health impact assessment of air pollution in the metropolitan region of Fortaleza, Ceará, Brazil. Atmos. Environ.; 2020; 241, 117751. [DOI: https://dx.doi.org/10.1016/j.atmosenv.2020.117751]
62. Martins, E.H.; de Souza Eicardi, M.; Nogarotto, D.C.; Pozza, S.A. Health and Economic Benefits of Lowering Particulate Matter (PM) Levels: Scenarios for a Southern Brazilian Metropolis. Aerosol Sci. Eng.; 2024; 9, pp. 1-12. [DOI: https://dx.doi.org/10.1007/s41810-024-00239-3]
63. Abe, K.C.; Miraglia, S.G.E.K. Universidade de São Paulo avaliação de impacto à saúde do programa de controle de poluição do ar por veículos automotores no município de São Paulo, Brasil. Rev. Bras. Ciências Ambient.; 2018; 47, pp. 61-73. [DOI: https://dx.doi.org/10.5327/Z2176-947820180310]
64. Ostro, B. World Health Organization. Outdoor Air Pollution: Assessing the Environmental Burden of Disease at National and Local Levels. World Health Organization. 2004; Available online: https://www.who.int/publications/i/item/9241591463 (accessed on 26 December 2024).
65. Vormittag, E.d.M.P.A.d.A.; Cirqueira, S.S.R.; Neto, H.W.; Saldiva, P.H.N. Análise do monitoramento da qualidade do ar no Brasil. Estud. Avançados; 2021; 35, pp. 7-30. [DOI: https://dx.doi.org/10.1590/s0103-4014.2021.35102.002]
66. IEMA. Instituto de Energia e Meio Ambiente. Dimensionamento da Rede Básica de Monitoramento da Qualidade do Ar no Brasil. 2024; Available online: https://energiaeambiente.org.br/produto/dimensionamento-da-rede-basica-de-monitoramento-da-qualidade-do-ar-no-brasil-cenarios-iniciais (accessed on 25 January 2025).
67. da Silva Júnior, F.M.R.; Honscha, L.; Brum, R.; Ramires, P.; Tavella, R.; Fernandes, C.; Penteado, J.; Bonifácio, A.; Volcão, L.; Santos, M. et al. Air quality in cities of the extreme south of Brazil. Ecotoxicol. Environ. Contam.; 2020; 15, pp. 61-67. [DOI: https://dx.doi.org/10.5132/eec.2020.01.08]
You have requested "on-the-fly" machine translation of selected content from our databases. This functionality is provided solely for your convenience and is in no way intended to replace human translation. Show full disclaimer
Neither ProQuest nor its licensors make any representations or warranties with respect to the translations. The translations are automatically generated "AS IS" and "AS AVAILABLE" and are not retained in our systems. PROQUEST AND ITS LICENSORS SPECIFICALLY DISCLAIM ANY AND ALL EXPRESS OR IMPLIED WARRANTIES, INCLUDING WITHOUT LIMITATION, ANY WARRANTIES FOR AVAILABILITY, ACCURACY, TIMELINESS, COMPLETENESS, NON-INFRINGMENT, MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE. Your use of the translations is subject to all use restrictions contained in your Electronic Products License Agreement and by using the translation functionality you agree to forgo any and all claims against ProQuest or its licensors for your use of the translation functionality and any output derived there from. Hide full disclaimer
© 2025 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
Abstract
Air pollution, particularly from coarse particulate matter (PM10), is a major public health concern, significantly contributing to respiratory and cardiovascular diseases, especially among vulnerable populations. In 2024, Brazil introduced a new air quality resolution (CONAMA Resolution No. 506/2024), aligning its ultimate goal with the World Health Organization’s 2021 guidelines while establishing specific timelines for the interim targets. However, these interim targets, set for 2025, 2033, and 2044, along with the absence of a deadline for the final target of 15 µg/m3, raise concerns about their adequacy in addressing the urgent health impacts of air pollution. This study evaluates the economic and public health benefits of accelerating these targets in the city of Rio Grande, a region characterized by an industrial and port-driven economy and an aging population particularly vulnerable to air pollution. Using health impact assessments, economic cost analyses, and mortality estimates, we modeled three scenarios with PM10 concentration limits of 30 µg/m3, 20 µg/m3, and 15 µg/m3, corresponding to the resolution’s 2033 and 2044 goals and the undated final target. Our findings indicate that achieving the 15 µg/m3 target by 2025 could prevent 2568 respiratory hospitalizations, 1551 cardiac hospitalizations, and 1128 air pollution-related deaths in Rio Grande, resulting in approximately BRL 7.3 million in healthcare savings. When extrapolated to cities with similar pollution profiles across Brazil, these results suggest substantial potential for reducing the health burdens and economic costs nationwide. This study underscores the urgent need to establish more ambitious timelines in Brazil’s air quality policies to maximize public health benefits and mitigate the economic impacts of air pollution.
You have requested "on-the-fly" machine translation of selected content from our databases. This functionality is provided solely for your convenience and is in no way intended to replace human translation. Show full disclaimer
Neither ProQuest nor its licensors make any representations or warranties with respect to the translations. The translations are automatically generated "AS IS" and "AS AVAILABLE" and are not retained in our systems. PROQUEST AND ITS LICENSORS SPECIFICALLY DISCLAIM ANY AND ALL EXPRESS OR IMPLIED WARRANTIES, INCLUDING WITHOUT LIMITATION, ANY WARRANTIES FOR AVAILABILITY, ACCURACY, TIMELINESS, COMPLETENESS, NON-INFRINGMENT, MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE. Your use of the translations is subject to all use restrictions contained in your Electronic Products License Agreement and by using the translation functionality you agree to forgo any and all claims against ProQuest or its licensors for your use of the translation functionality and any output derived there from. Hide full disclaimer
Details





1 Faculty of Medicine, Federal University of Rio Grande, Rio Grande 96200-190, Brazil;
2 Institute of Biological Sciences, Federal University of Rio Grande, Rio Grande 996201-900, Brazil;
3 Institute of Environmental, Chemical and Pharmaceutical Sciences, Federal University of São Paulo, Diadema 09972-270, Brazil
4 Faculty of Medicine, Federal University of Rio Grande, Rio Grande 96200-190, Brazil;