Abstract

Brown adipose tissue (BAT) contains many immune cells. The presence of macrophages, monocytes, dendritic cells, T cells, B cells, and mast cells was documented in BAT. However, in comparison to white adipose tissue, relatively little is known on the impact of immune cells on BAT function. By directly interacting with BAT stromal cells, or by secreting pro- and anti-inflammatory mediators, immune cells modulate BAT activation and subsequently influence on adaptative thermogenesis and heat generation. In the current manuscript, we will focus on the diversity and functions of BAT immune cells.

Details

Title
Immune cell involvement in brown adipose tissue functions
Author
Bertola, Adeline 1 ; Gallerand, Alexandre 1 ; Ivanov, Stoyan 1   VIAFID ORCID Logo 

1  Université Côte d’Azur, CNRS, LP2M , Nice , France 
Publication year
2022
Publication date
2022
Publisher
Oxford University Press
e-ISSN
27542483
Source type
Scholarly Journal
Language of publication
English
DOI
https://doi.org/10.1093/discim/kyac007
ProQuest document ID
3190865357
Copyright
© The Author(s) 2022. Published by Oxford University Press on behalf of the British Society for Immunology. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.