It appears you don't have support to open PDFs in this web browser. To view this file, Open with your PDF reader
Abstract
China and the world are facing severe population aging and an increasing burden of age-related diseases. Aging of the brain causes major age-related brain diseases, such as neurodegenerative diseases and stroke. Identifying biomarkers for the effective assessment of brain aging and establishing a brain aging assessment system could facilitate the development of brain aging intervention strategies and the effective prevention and treatment of aging-related brain diseases. Thus, experts from the Aging Biomarker Consortium (ABC) have combined the latest research results and practical experience to recommend brain aging biomarkers and form an expert consensus, aiming to provide a basis for assessing the degree of brain aging and conducting brain-aging-related research with the ultimate goal of improving the brain health of elderly individuals in both China and the world.
You have requested "on-the-fly" machine translation of selected content from our databases. This functionality is provided solely for your convenience and is in no way intended to replace human translation. Show full disclaimer
Neither ProQuest nor its licensors make any representations or warranties with respect to the translations. The translations are automatically generated "AS IS" and "AS AVAILABLE" and are not retained in our systems. PROQUEST AND ITS LICENSORS SPECIFICALLY DISCLAIM ANY AND ALL EXPRESS OR IMPLIED WARRANTIES, INCLUDING WITHOUT LIMITATION, ANY WARRANTIES FOR AVAILABILITY, ACCURACY, TIMELINESS, COMPLETENESS, NON-INFRINGMENT, MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE. Your use of the translations is subject to all use restrictions contained in your Electronic Products License Agreement and by using the translation functionality you agree to forgo any and all claims against ProQuest or its licensors for your use of the translation functionality and any output derived there from. Hide full disclaimer
Details


1 Department of Neurology and Centre for Clinical Neuroscience, Daping Hospital, Third Military Medical University , Chongqing 400042 , China
2 National Clinical Research Center for Geriatric Diseases, Xuanwu Hospital, Capital Medical University , Beijing 100053 , China
3 Department of Neurology and Institute of Neurology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine , Shanghai 200025 , China
4 Department of Neurology, Union Hospital of Fujian Medical University , Fuzhou 350001 , China
5 Department of Neurology, First Affiliated Hospital, Shanxi Medical University , Taiyuan 030001 , China
6 Department of Gerontology, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine , Shanghai 200233 , China
7 Department of Neurology and Neurological Rehabilitation, Shanghai Disabled Persons’ Federation Key Laboratory of Intelligent Rehabilitation Assistive Devices and Technologies, Yangzhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), Tongji University, School of Medicine , Shanghai 200092 , China
8 Institute on Aging and Brain Disorders, The First Affiliated Hospital of USTC, Hefei National Laboratory for Physical Sciences at the Microscale, Division of Life Sciences and Medicine, University of Science and Technology of China , Hefei 230026 , China
9 Department of Cardiology, Shanghai Tongji Hospital, Tongji University School of Medicine , Shanghai 200092 , China
10 Shanghai Key Laboratory of Maternal Fetal Medicine, Clinical and Translational Research Center of Shanghai First Maternity and Infant Hospital, Frontier Science Center for Stem Cell Research, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Sciences and Technology, Tongji University , Shanghai 200092 , China
11 State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences , Beijing 100101 , China
12 Institute of Aging, Key Laboratory of Alzheimer’s Disease of Zhejiang Province, Zhejiang Clinical Research Center for Mental Disorders, School of Mental Health and The Affiliated Kangning Hospital, Wenzhou Medical University, Oujiang Laboratory , Wenzhou, Zhejiang 325035 , China
13 Department of Neurology & Innovation Center for Neurological Disorders, Xuanwu Hospital, Capital Medical University, National Center for Neurological Disorders , Beijing 100053 , China
14 Department of Gerontology, Shengjing Hospital of China Medical University, Shenyang 110000 , China
15 Department of Radiology, Tongji Hospital, Shanghai Frontiers Science Center of Nanocatalytic Medicine, The Institute for Biomedical Engineering & Nano Science, School of Medicine, Tongji University , Shanghai 200092 , China
16 Shanghai Key Laboratory of Anesthesiology and Brain Functional Modulation, Translational Research Institute of Brain and Brain-Like Intelligence, Shanghai Fourth People’s Hospital, Tongji University , Shanghai 200434 , China
17 Faculty of Life and Health Sciences, Shenzhen Institute of Advanced Technology, Chinese Academy of Science , Shenzhen 518055 , China
18 Department of Neurology, Zhongnan Hospital of Wuhan University , Wuhan 430071 , China
19 CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation , Beijing 100101 , China
20 Translational Medical Center for Stem Cell Therapy, Shanghai East Hospital, School of Medicine, Tongji University , Shanghai 200120 , China
21 Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, School of Medicine, Xiamen University , Xiamen 361102 , China
22 State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University , Beijing 100875 , China
23 Hunan Key Laboratory of Molecular Precision Medicine, Department of Critical Care Medicine, Xiangya Hospital, Central South University , Changsha 410008 , China
24 Center for Translational Neurodegeneration and Regenerative Therapy, Tongji Hospital affiliated to Tongji University School of Medicine , Shanghai 200072 , China
25 University of Chinese Academy of Sciences , Beijing 100049 , China
26 Stem Cell Translational Research Center, Tongji Hospital, Tongji University School of Medicine , Shanghai 200065 , China
27 Department of Neurology and Center for Clinical Neuroscience, Daping Hospital, Third Military Medical University , Chongqing 400042 , China
28 Collaborative Innovation Center for Brain Science, School of Life Science and Technology, Tongji University , Shanghai 200092 , China