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© 2023. This work is published under https://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.

Abstract

Chronic constipation is a common gastrointestinal disorder, and its management often requires long-term use of laxatives. This review addresses the differences between two commonly used laxatives, lactulose and bisacodyl. The efficacy, side effect profiles, tolerance development, use in special populations, drug interactions, contraindications, and impacts on patient compliance and quality of life of these two laxatives are compared. Both lactulose and bisacodyl are effective in improving bowel movements and are widely used in clinical practice. However, lactulose might present a more favorable profile for certain patient populations when considering factors such as side effect profile, patient compliance, quality of life, and cost-effectiveness. Primary care physicians should consider these aspects when choosing the most appropriate treatment option for their patients, always considering individual patient characteristics and preferences.

Details

Title
Comparative Evaluation of Lactulose and Bisacodyl in the Management of Chronic Constipation: Efficacy, Safety, and Patient Preferences
Author
Dabak, Mustafa Reşat  VIAFID ORCID Logo  ; Güler, Kerim  VIAFID ORCID Logo 
Pages
335-340
Section
Review
Publication year
2023
Publication date
Dec 2023
Publisher
Galenos Publishing House
ISSN
25479431
Source type
Scholarly Journal
Language of publication
English; Turkish
ProQuest document ID
3198162318
Copyright
© 2023. This work is published under https://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.