Correction: Kim et al. Novel Gene Polymorphisms for Stable Warfarin Dose in a Korean Population: Genome-Wide Association Study. Biomedicines 2023, 11, 2308

Text Correction

There was an error in the original publication [1]. We applied a relaxed p-value threshold of 5 × 10⁻⁷, which was mentioned in the Results section. However, this threshold was not stated in the Abstract and Conclusions sections, which may mislead readers into assuming that the conventional genome-wide significance threshold (5 × 10⁻⁸) was used.

A correction has been made to the Abstract:

GWAS was performed with a lenient threshold of 5 × 10⁻⁷ to identify associations between genotypes and the warfarin maintenance dose, by comparing the allele frequency of genetic variants between individuals.

A correction has been made to the Conclusions:

Our GWAS has uncovered three previously unreported genetic variants (FRAS1 rs4386623, FAM201A rs1890109, and NKX2-6 rs310279) that demonstrate associations at a relaxed significance threshold with stable warfarin dose requirements in heart valve replacement patients.

The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.

Footnotes

Disclaimer/Publisher’s Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content.

References

Reference

1. Kim, J.S.; Lee, S.; Yee, J.; Park, K.; Jang, E.J.; Chang, B.C.; Gwak, H.S. Novel Gene Polymorphisms for Stable Warfarin Dose in a Korean Population: Genome-Wide Association Study. Biomedicines; 2023; 11, 2308. [DOI: https://dx.doi.org/10.3390/biomedicines11082308] [PubMed: https://www.ncbi.nlm.nih.gov/pubmed/37626805]