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© 2024. This work is published under http://creativecommons.org/licenses/by/4.0/ (the "License"). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.

Abstract

Background

Endoscopic biliary stenting is a standard treatment for biliary strictures after liver transplantation. Plastic stents are often replaced before stent dysfunction to prevent the development of cholangitis and jaundice. Therefore, the precise duration of stent patency is unclear.

Methods

We compared retrospectively the stent patency period and stent dysfunction rate between inside stents (IS) and conventional plastic stents (PS) in 48 patients with post‐transplant strictures, distinguishing endoscopic biliary stenting with and without stent dysfunction at stent replacement.

Results

In observations focused on the first treatment, the median patency periods were 369 days for IS (n = 18) and 154 days for PS (n = 30; p = 0.01), significantly longer for IS. The 1‐year cholangitis incidence rate was lower for IS (20% vs. 43%, p = 0.04). Additionally, no stent dislocation was observed for IS, but this occurred for 33.3% of PS (p = 0.004). Comparing all endoscopic biliary stenting, including second and subsequent procedures, IS again had a longer patency period than PS (356 days, n = 89, vs. 196 days, n = 127, p = 0.009).

Conclusions

IS had a significantly longer patency period than PS, suggesting that IS replacement could be reduced to once per year for patients who prefer less frequent stent replacement.

Details

Title
Clinical usefulness of inside stents in anastomotic biliary strictures after liver transplantation
Author
Kugiyama, Naotaka 1 ; Hashigo, Shunpei 1 ; Nagaoka, Katsuya 1 ; Watanabe, Takehisa 1 ; Ushijima, Shinya 1 ; Uramoto, Yukiko 1 ; Yoshinari, Motohiro 1 ; Morinaga, Jun 2 ; Gushima, Ryosuke 1 ; Tateyama, Masakuni 1 ; Tanaka, Motohiko 3 ; Naoe, Hideaki 1 ; Sugawara, Yasuhiko 4 ; Hibi, Taizo 4 ; Tanaka, Yasuhito 1   VIAFID ORCID Logo 

 Department of Gastroenterology and Hepatology, Kumamoto University Hospital, Kumamoto, Japan 
 Department of Clinical Investigation, Kumamoto University Hospital, Kumamoto, Japan 
 Department of Public Health and Welfare, Kumamoto, Japan 
 Department of Pediatric Surgery and Transplantation, Kumamoto University Hospital, Kumamoto, Japan 
Section
ORIGINAL ARTICLES
Publication year
2024
Publication date
Apr 1, 2024
Publisher
John Wiley & Sons, Inc.
ISSN
26924609
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
3212681110
Copyright
© 2024. This work is published under http://creativecommons.org/licenses/by/4.0/ (the "License"). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.