Risk factors for venous thrombosis after hip arthroplasty: a meta-analysis

Abstract

Background

Venous thrombosis is a common complication after hip arthroplasty.

Methods

PubMed, Embase, the Cochrane Library, and Web of Science were searched for case-control studies on risk factors for venous thrombosis after hip arthroplasty up to September 14, 2023. Data analysis was performed using Stata15.0.

Results

This meta-analysis included 15 case-control studies, comprising 17,909 participants, including 1149 patients with venous thrombosis and 16,760 patients without venous thrombosis. The univariate meta-analysis results revealed that age over 70 years old, hypertension, BMI ≥ 25, operation time, stroke, and use of mechanical prophylaxis alone were risk factors for venous thrombosis after hip arthroplasty. Multivariate analysis showed that female, age > 70 years, BMI ≥ 25, cemented prosthesis, and a history of venous thrombosis were the risk factors for venous thrombosis after hip arthroplasty.

Conclusions

This study suggests that female sex, age over 70 years, hypertension, a BMI of 25 or higher, duration of operation, stroke, mechanical prevention only, use of a cemented prosthesis, and a history of venous thrombosis are risk factors for venous thrombosis following hip arthroplasty.

Clinical trial number

not applicable.