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Title
Trimethylamine-N-Oxide Impedes Late Endothelial Progenitor Cell–Mediated Revascularization by Triggering Mitochondrial Apoptosis via Suppression of MnSOD
Author
Shao, Yijia 1
; Sun, Jiapan 2
; Liu, Xiang 3
; Liu, Xing 4
; Wu, Fang 1
; Wang, Zhichao 5
; Xu, Shiyue 6
; Long, Chen 7
1 Department of Geriatrics The First Affiliated Hospital Sun Yat-sen University Guangzhou China
2 Department of Traditional Chinese Medicine The Seventh Affiliated Hospital Sun Yat-sen University Shenzhen China
3 Department of Cardiac Surgery Guangdong Cardiovascular Institute Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences) Southern Medical University Guangzhou China
4 Department of Cardiology The Third Affiliated Hospital Sun Yat-sen University Guangzhou China
5 The International Medical Department of Shenzhen Hospital Southern Medical University Shenzhen China
6 Department of Hypertension and Vascular Diseases The First Affiliated Hospital Sun Yat-sen University Guangzhou China
7 The International Medical Department of Shenzhen Hospital Southern Medical University Shenzhen China; National Clinical Research Center of Cardiovascular Diseases Fuwai Hospital Chinese Academy of Medical Sciences Shenzhen China
; Sun, Jiapan 2
; Liu, Xiang 3
; Liu, Xing 4
; Wu, Fang 1
; Wang, Zhichao 5
; Xu, Shiyue 6
; Long, Chen 7
1 Department of Geriatrics The First Affiliated Hospital Sun Yat-sen University Guangzhou China
2 Department of Traditional Chinese Medicine The Seventh Affiliated Hospital Sun Yat-sen University Shenzhen China
3 Department of Cardiac Surgery Guangdong Cardiovascular Institute Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences) Southern Medical University Guangzhou China
4 Department of Cardiology The Third Affiliated Hospital Sun Yat-sen University Guangzhou China
5 The International Medical Department of Shenzhen Hospital Southern Medical University Shenzhen China
6 Department of Hypertension and Vascular Diseases The First Affiliated Hospital Sun Yat-sen University Guangzhou China
7 The International Medical Department of Shenzhen Hospital Southern Medical University Shenzhen China; National Clinical Research Center of Cardiovascular Diseases Fuwai Hospital Chinese Academy of Medical Sciences Shenzhen China
Editor
Youakim Saliba
Publication year
2025
Publication date
2025
ISSN
17555914
e-ISSN
17555922
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
3225275770
Copyright
Copyright © 2025 Yijia Shao et al. Cardiovascular Therapeutics published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution License (the “License”), which permits use, distribution and reproduction in any medium, provided the original work is properly cited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. https://creativecommons.org/licenses/by/4.0/





