Abstract

摘要:

<正>目前用于治疗慢性乙型肝炎 (CHB) 的药物主要为干扰素 (IFN) 及核苷 (酸) 类药物 (NAs) 两类[1]。IFN治疗的优势包括疗程有限、应答更持久以及不产生耐药,也是目前有望提高功能性治愈率、达到理想治疗终点的主要药物[2]。但IFN不良反应较多,极少数可出现严重不良反应,如免疫性血小板减少性紫癜及血栓性血小板减少性紫癜 (thrombotic thrombocytopenic purpura,TTP) [3]。通过报道1例可能与PEG-IFNα-2a治疗CHB相关的致死性TTP,以提醒临床医生加以注意。

Details

Title
聚乙二醇干扰素治疗慢性乙型肝炎诱发血栓性血小板减少性紫癜1例报告
Author
王欣茹; 肖丽; 耿爱文; 咸建春
Pages
2534-2536
Section
Case reports
Publication year
2020
Publication date
2020
Publisher
Journal of Clinical Hepatology
ISSN
10015256
e-ISSN
20973497
Source type
Scholarly Journal
Language of publication
Chinese
DOI
https://doi.org/10.3969/j.issn.1001-5256.2020.11.028
ProQuest document ID
3240110752
Copyright
© 2020. This work is published under https://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.