Abstract

肝衰竭是多种因素引起的肝脏损害,而维生素K1治疗肝衰竭凝血功能障碍一直存在争议。回顾了各国肝衰竭诊疗指南以及维生素K1治疗肝病凝血功能障碍的文献,分析得出盲目应用维生素K1不能改善肝病患者凝血功能,但肝衰竭时维生素K缺乏且伴有凝血功能障碍时,应用维生素K1可能是必要的。另外,胆汁淤积状态可作为独立因素考虑,但有待于进一步验证。

Alternate abstract:

Liver failure is a type of liver injury caused by a variety of factors, and there are still controversies over the clinical effect of vitamin K1 in the treatment of coagulopathy of liver failure. This article reviews the guidelines for the diagnosis and treatment of liver failure in various countries and the articles on vitamin K1 in the treatment of coagulopathy of liver diseases. It is concluded that blind application of vitamin K1 cannot improve the coagulation function of patients with liver disease; however, vitamin K1 is necessary for patients with vitamin K deficiency and coagulopathy during liver failure. In addition, the state of cholestasis may be considered an independent factor, but further studies are needed for verification.

Details

Title
维生素K1治疗肝衰竭凝血功能障碍的研究进展
Author
熊壮; 刘扬扬; 霍少凯; 宫嘉莲; 金天一; 王强; 王慧林; 刘铁军; 冷炎
Pages
2099-2103
Section
Reviews
Publication year
2019
Publication date
2019
Publisher
Journal of Clinical Hepatology
ISSN
10015256
e-ISSN
20973497
Source type
Scholarly Journal
Language of publication
Chinese
ProQuest document ID
3240294462
Copyright
© 2019. This work is published under https://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.