Details
Title
Equivalence of SYN008 versus omalizumab in patients with refractory chronic spontaneous urticaria: A multicenter, randomized, double-blind, parallel-group, active-controlled phase III study
Author
Li, Jingyi 1 ; Liang Yunsheng 2 ; Feng Wenli 3 ; Deng Liehua 4 ; Fang, Hong 5 ; Ji, Chao 6 ; Lin Youkun 7 ; Zhang Furen 8 ; Xia Rushan 9 ; Zhang, Chunlei 10 ; Guo Shuping 11 ; Mao, Lin 12 ; Li, Yanling 13 ; Zhang Shoumin 14 ; Kang, Xiaojing 15 ; Chen, Liuqing 16 ; Song, Zhiqiang 17 ; Xu, Yao 18 ; Li, Chengxin 19 ; Han, Xiuping 20 ; Guo Guoxiang 21 ; Guo, Qing 22 ; Duan Xinsuo 23 ; Li, Jie 24 ; Su, Juan 24 ; Li, Shanshan 25 ; Sun, Qing 26 ; Tao, Juan 27 ; Ding Yangfeng 28 ; Deng Danqi 29 ; Li Fuqiu 30 ; Suo Haiyun 31 ; Wu Shunquan 31 ; Qiu Jingbo 31 ; Luo Hongmei 31 ; Li, Linfeng 32 ; Li Ruoyu 33
1 Department of Dermatology, West China Hospital Sichuan University, Chengdu, Sichuan 610041, China
2 Dermatology Hospital of Southern Medical University, Guangzhou, Guangdong 510091, China
3 Department of Dermatology, Second Hospital of Shanxi Medical University, Taiyuan, Shanxi 030001, China
4 Department of Dermatology, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong 510630, China
5 Department of Dermatology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310003, China
6 Department of Dermatology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian 350005, China
7 Department of Dermatology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, China
8 Shandong Province Dermatology Hospital, Weifang, Shandong 261042, China
9 Department of Dermatology, Wuxi Second People’s Hospital, Wuxi, Jiangsu 214002, China
10 Department of Dermatology, Peking University Third Hospital, Beijing 100191, China
11 Department of Dermatology, First Hospital of Shanxi Medical University, Taiyuan, Shanxi 030001, China
12 Department of Dermatology, Chongqing Traditional Chinese Medicine Hospital, Chongqing 400011, China
13 Department of Dermatology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei 050061, China
14 Department of Dermatology, Henan Provincial People’s Hospital, Zhengzhou, Henan 450003, China
15 Department of Dermatology, People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang 830001, China
16 Department of Dermatology, Wuhan Hospital of Traditional Chinese and Western Medicine/Wuhan No.1 Hospital, Wuhan, Hubei 430022, China
17 Department of Dermatology, The Southwest Hospital of AMU, Chongqing 400038, China
18 Institute of Dermatology, Chinese Academy of Medical Sciences, Beijing 100730, China
19 Department of Dermatology, Chinese PLA General Hospital, Beijing 100853, China
20 Department of Dermatology, Shengjing Hospital of China Medical University, Shenyang, Liaoning 110004, China
21 Department of Dermatology, Baogang Hospital of Inner Mongolia, Baotou, Inner Mongolia 014017, China
22 Department of Dermatology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong 510120, China
23 Department of Dermatology, Affiliated Hospital of Chengde Medical University, Chengde, Hebei 067000, China
24 Department of Dermatology, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China
25 Department of Dermatology, The First Bethune Hospital of Jilin University, Changchun, Jilin 130031, China
26 Department of Dermatology, Qilu Hospital of Shandong University, Jinan,Shandong 266034, China
27 Department of Dermatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China
28 Department of Dermatology, Shanghai Skin Disease Hospital, Tongji University School of Medicine, Shanghai 200443, China
29 Department of Dermatology, The Second Affiliated Hospital of Kunming Medical College, Kunming 650101, China
30 Department of Dermatology, The Second Norman Bethune Hospital of Jilin University, Changchun 130021, China
31 CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd, Shijiazhuang, Hebei 050035, China
32 Department of Dermatology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China
33 Department of Dermatology, Peking University First Hospital, Beijing 100034, China
1 Department of Dermatology, West China Hospital Sichuan University, Chengdu, Sichuan 610041, China
2 Dermatology Hospital of Southern Medical University, Guangzhou, Guangdong 510091, China
3 Department of Dermatology, Second Hospital of Shanxi Medical University, Taiyuan, Shanxi 030001, China
4 Department of Dermatology, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong 510630, China
5 Department of Dermatology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310003, China
6 Department of Dermatology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian 350005, China
7 Department of Dermatology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, China
8 Shandong Province Dermatology Hospital, Weifang, Shandong 261042, China
9 Department of Dermatology, Wuxi Second People’s Hospital, Wuxi, Jiangsu 214002, China
10 Department of Dermatology, Peking University Third Hospital, Beijing 100191, China
11 Department of Dermatology, First Hospital of Shanxi Medical University, Taiyuan, Shanxi 030001, China
12 Department of Dermatology, Chongqing Traditional Chinese Medicine Hospital, Chongqing 400011, China
13 Department of Dermatology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei 050061, China
14 Department of Dermatology, Henan Provincial People’s Hospital, Zhengzhou, Henan 450003, China
15 Department of Dermatology, People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang 830001, China
16 Department of Dermatology, Wuhan Hospital of Traditional Chinese and Western Medicine/Wuhan No.1 Hospital, Wuhan, Hubei 430022, China
17 Department of Dermatology, The Southwest Hospital of AMU, Chongqing 400038, China
18 Institute of Dermatology, Chinese Academy of Medical Sciences, Beijing 100730, China
19 Department of Dermatology, Chinese PLA General Hospital, Beijing 100853, China
20 Department of Dermatology, Shengjing Hospital of China Medical University, Shenyang, Liaoning 110004, China
21 Department of Dermatology, Baogang Hospital of Inner Mongolia, Baotou, Inner Mongolia 014017, China
22 Department of Dermatology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong 510120, China
23 Department of Dermatology, Affiliated Hospital of Chengde Medical University, Chengde, Hebei 067000, China
24 Department of Dermatology, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China
25 Department of Dermatology, The First Bethune Hospital of Jilin University, Changchun, Jilin 130031, China
26 Department of Dermatology, Qilu Hospital of Shandong University, Jinan,Shandong 266034, China
27 Department of Dermatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China
28 Department of Dermatology, Shanghai Skin Disease Hospital, Tongji University School of Medicine, Shanghai 200443, China
29 Department of Dermatology, The Second Affiliated Hospital of Kunming Medical College, Kunming 650101, China
30 Department of Dermatology, The Second Norman Bethune Hospital of Jilin University, Changchun 130021, China
31 CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd, Shijiazhuang, Hebei 050035, China
32 Department of Dermatology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China
33 Department of Dermatology, Peking University First Hospital, Beijing 100034, China
Pages
2040-2042
Section
Correspondence
Publication year
2025
Publication date
Aug 2025
ISSN
03666999
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
3241404359
Copyright
Copyright © 2025 The Chinese Medical Association, produced by Wolters Kluwer, Inc. under the CC-BY-NC-ND license. This work is published under http://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.