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Environ Health Prev Med (2010) 15:229235 DOI 10.1007/s12199-009-0132-7
REGULAR ARTICLE
Abdominal circumference should not be a required criterion for the diagnosis of metabolic syndrome
Kiyoshi Shibata Sadao Suzuki Juichi Sato
Isao Ohsawa Shinichi Goto Masaru Hashiguchi
Shinkan Tokudome
Received: 23 July 2009 / Accepted: 25 December 2009 / Published online: 4 February 2010 The Japanese Society for Hygiene 2010
AbstractBackground Metabolic syndrome (MetS) is an established concept. However, it is characterized by a number of different denitions as well as different cut-off points (COPs) for waist circumference (WC) and different modes for incorporating WC into the diagnostic criteria. Methods Abdominal ultrasonography was performed in 2,333 subjects who also underwent comprehensive medical examinations between April and July 2006. The odds ratios for the number of MetS components were calculated by taking central obesity status into account and considering concurrent fatty liver as an independent variable. We compared the areas under the receiver operating characteristic (ROC) curves for fatty liver and MetS using several MetS criteria.
K. Shibata (&) M. Hashiguchi
Kasugai City Medical Center, 1-1-7 Chuodai, Kasugai, Aichi 487-0011, Japane-mail: [email protected]
K. Shibata S. Suzuki S. Tokudome
Department of Public Health, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan
J. SatoDepartment of General Medicine,Nagoya University Hospital, Nagoya, Japan
I. OhsawaDepartment of Health Science,Aichi Gakuin University, Nisshin, Aichi, Japan
S. GotoDepartment of Medical Laboratory, Kasugai Municipal Hospital, Kasugai, Japan
S. TokudomeNational Institute of Health and Nutrition, Tokyo, Japan
Results Regardless of the WC criterion selected, we observed a strong linear trend for an association (trend P \ 0.0001) between MetS and the number of components.
The odds ratio (OR) of subjects without central obesity but with all three MetS components was 9.69 (95% condence interval 3.1130.2) in men and 55.3 (6.34483) in women. The COP for the largest area under the curve in men and women was C82 cm (OR 0.701) and C77 cm (OR 0.699), respectively, when WC was considered as a component. When WC distribution is taken into consideration, practical and appropriate COPs should be C85 cm for men and C80 cm for women.
Conclusion We suggest that a WC of C85 cm for men and C80 cm for women would be optimal COPs for the central obesity criteria in the Japanese population....