Colorectal cancer in hyperplastic polyposis syndrome: In search of the polyp of origin

Abstract

From: 14th Annual Meeting of the Collaborative Group of the Americas on Inherited Colorectal Cancer Dallas, TX, USA 12-13 October 2010 Author details 1-Department of Molecular and Cellular Pathology, University of Queensland Centre for Clinical Research, Herston, QLD 4006, AustraliaEMPTY 2-Familial Cancer Laboratory, Queensland Institute for Medical Research, Herston, QLD 4006, AustraliaEMPTY 3-Envoi Pathology, Herston, QLD 4006, AustraliaEMPTY 4-Centre for MEGA Epidemiology, School of Population Health, University of Melbourne, Carlton, VIC 3053, AustraliaEMPTY 5-Division of Human Genetics, Ohio State University, Columbus, OH 43221, USAEMPTY 6-Department of Gastroenterology, Middlemore Hospital, Auckland 1640, New ZealandEMPTY Supplemental Information: Meeting abstracts - A single PDF containing all abstracts in this supplement is available at http://www.biomedcentral.com/content/files/pdf/1897-4287-9-S1-full.pdf.EMPTY Background Hyperplastic polyposis syndrome (HPS) is a colorectal cancer (CRC) predisposition of unknown genetic aetiology that is characterised by the presence of multiple serrated polyps throughout the colon, and an increased risk of having a first-degree relative with CRC [1-3].