Abstract

A 3-year-old female patient developed chorea possibly due to an interaction between phenytoin, phenobarbital and clobazam used for generalized tonic clonic seizures. Phenytoin withdrawal resulted in recovery within 24 hours. Post reaction computerized tomography (CT)-scan of brain was normal. Combined use of anti-seizure drugs and interactions between them may be responsible for the reaction. Therapeutic drug monitoring is important while prescribing two or more anti-seizure drugs. [PUBLICATION ABSTRACT]

Details

Title
Phenytoin induced chorea in a pediatric patient: An interaction between phenytoin, phenobarbital and clobazam
Author
Barvaliya, Manish; Sanmukhani, Jayesh; Patel, Tejas; Tripathi, C
Pages
731-732
Publication year
2011
Publication date
Nov/Dec 2011
Publisher
Medknow Publications & Media Pvt. Ltd.
ISSN
02537613
e-ISSN
19983751
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
918640401
Copyright
Copyright Medknow Publications & Media Pvt Ltd Nov/Dec 2011