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Abstract
Background We have recently reported that the dietary supplement Meltdown® (Vital Pharmaceuticals) increases plasma norepinephrine (NE), epinephrine (EPI), glycerol, and free fatty acids (FFA), as well as metabolic rate in healthy men [1]. Methods Ten exercise trained men (age = 24 ± 4 yrs; BMI = 25 ± 3 kg·m-2; body fat = 9 ± 3%; mean ± SD) and 10 exercise trained women (age = 22 ± 2 yrs; BMI = 23 ± 3 kg·m-2; body fat = 23 ± 5%; mean ± SD) ingested Meltdown® or a placebo, in a random order, double blind cross-over design, with one week separating conditions. Intervention studies should be undertaken to determine the impact of this dietary supplement on weight/fat loss, while monitoring hemodynamic variables to ensure safety of treatment. 1.
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