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In their review, Elihu Estey and Hartmut Donner (Nov 25, p 1894): cite the 1999 paper by Gundestrup and Storm,2 reporting a 5.1-fold increased incidence of acute myeloid leukaemia in 3000 Danish mate cockpit crew, a finding arbitrarily attributed to increased cosmic ray exposure. However, in 2003, Pukkala and colleagues showed in the largest study published to date that the incidence of acute myeloid leukaemia was...