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A 3-day-old male neonate developed hyponatraemia during treatment with aminophylline.
The neonate, who was born at 26 weeks of gestation, started receiving IV aminophylline at a loading dose of 8 mg/kg followed by maintenance dose of 2.5 mg/kg every 12 hours, on day 1 of life to treat apnea of prematurity. On day 3 of life, his serum sodium level reduced...
