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A 77-year-old woman developed spontaneous splenic rupture following concomitant administration of amiodarone, lercanidipine and rivaroxaban [routes and time to reaction onset not stated; not ail indications stated].
The woman, who had a significant medical history of major depression, glaucoma, moderate alcohol intake, hypertension and dyslipidaemia was admitted for a trans-oesophageal echocardiogram-guided direct current cardioversion. Her medication regimen at the time of admission consisted of rivaroxaban 20mg daily, amiodarone 200mg daily, lercanidipine 20mg daily, metoprolol, atorvastatin, esomeprazole, quetiapine, eprosartan and latanoprost eyedrops. After the cardioversion, she was noted to have low oxygen...