Angiolymphoid hyperplasia with eosinophilia on penis in HIV-positive patient: An unusual presentation

Abstract

Cutaneous examination revealed a solitary, sub-preputial pink, flesh-colored non-foul-smelling exophytic polypoid eroded indurated growth with moist surface measuring about 1.5 x 1 cm over ventrolateral aspect of penile shaft, [Figure 1]a which was non-tender, non-friable, did not bleed on manipulation and was covered with scant yellowish slough, without significant inguinal lymphadenopathy. Histology shows a well-defined area of vascular proliferation in the dermis and/or subcutis, with large epithelioid or histocytoid endothelial cells containing abundant cytoplasm, often with vacuoles and an infiltrate of variable numbers of eosinophils and lymphocytes.