Content area
Full text
Abstract
Streptococcus Viridans can cause diseases of the heart valves known as Infective Endocarditis, in addition to causing periodontal disease. As an adjunct to mechanical plaque control, mouthwashes aid in the control and prevention of dental plaque biofilm. The aim of this study was to find out whether there is any difference in the antimicrobial efficacy between Chlorhexidine and hyaluronic acid on the CFUs of Streptococcus Viridans.
Commercially available Streptococcus Viridans isolates obtained from the American Type Culture Collection (ATCC 12392, USA) were used in this study. 0.1 mL volume of the prepared bacterial suspension was added to 3 serial dilutions (100%, 50% and 25% concentration) of Chlorhexidine mouthwash (CHX) and Hyaluronic acid mouthwash (HA) including NaCI (0.9%) which was the control. Following the incubation (for 0.5, 1, 1.5 and 5 min, at 37 °C).
Chlorhexidine at 0.2% concentration showed significant reductions of CFUs/ml; (1,859 at 30 seconds, 1,105 at 1 minute, 936 at 1.5 minutes and 234 at 5 minutes) as compared to the control (CFU >106). Hyaluronic acid did not have an effect on the number of colonies with >106 CFUs/ml in all concentrations.
Hyaluronic acid did not exhibit any antimicrobial effect on Streptococcus Viridans.
Experimental article (J Int Dent Med Res 2022; 15(2): 485-489)
Keywords: Viridans Streptococcus, Endocarditis, Chlorhexidine, Hyaluronic Acid Mouthwashes.
Received date: 05 December 2021_Accept date: 12 January 2022
Introduction
Periodontitis is a condition where there is a loss of attachment of the periodontal tissues from the tooth structure.1 Periodontitis is the sixth most common human disease, and it is estimated to affect 11.2% of the global population. Periodontal disease is the leading cause of tooth loss with a global prevalence of about 90%. In the United States of America (USA) alone, 80% of its adults have experienced some form of periodontal disease which is more prevalent in individuals with low-income and non-educated levels. The consequences of untreated periodontal disease can have a devastating effect on the remaining dentition that could lead to halitosis, gingival bleeding, pathological migration of teeth, periodontal disease, tooth loss and aesthetic disharmony. Periodontal disease can also contribute to systemic diseases and a lot of evidence supports this association between periodontal and systemic diseases.2"4
The possible direct and indirect mechanisms related to the link between...