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ABSTRACT:
Chemical reagents bring about various types of changes in organic molecules to yield products of immense value. A few of the most important and widely used inorganic metals, non-metals and reagents based on them in organic name reactions have been discussed in this review
KEYWORDS: Organic name reactions, Rearrangements, Inorganic reagents, Condensation, Coupling.
1. INTRODUCTION:
There are a large number of organic reactions and molecular rearrangements which are of wide synthetic importance and applications and hence associated with the names of their discoverers. Organic reactions involve reagents and substrates. A group of compounds serve as substrates for a particular type of reaction when treated with a specific reagent.
A reagent is a "substance or compound that is added to a system in order to bring about a chemical reaction". In organic chemistry, reagents are compounds or mixtures, usually composed of inorganic or small organic molecules that are used to affect a transformation on an organic substrate. Examples of organic reagents include the Collins reagent, Fenton's reagent, and Grignard reagent. There are also analytical reagents which are used to confirm the presence of another substance. Examples of these are Fehling's reagent, Millon's reagent and Tollens' reagent. Nowadays a plenty of reagents for modern organic synthesis are available to the organic chemist to choose among and carry out the reaction smoothly to the desired product on both laboratory and industrial scales. The purpose of this review is to highlight some of the applications of inorganic reagents in organic name reactions.
Inorganic chemicals are substances of mineral origin that do not contain carbon in their molecular structure with the exception of carbon oxides and carbon disulphide or the compounds containing one or more metal atoms are considered to be inorganic.
Transition metal-catalyzed cross-coupling reactions of organometallic reagents with organic electrophiles represent one of the most powerful methods for the construction of carbon-carbon bonds. The application of a variety of inorganic oxidizing agents to organic substrates has broadened considerably the selectivity with which such oxidations may be carried out. The availability of a wide range of complex hydride reducing agents has greatly simplified the problem of selective reduction of functional groups. The technique of catalytic hydrogenation can be applied almost universally to the unsaturated systems, and...