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Elderly patients initiating treatment with gabapentin or pregabalin appear to have an increased risk of atrial fibrillation, according to study results reported in Drug Safety, although "this association should be confirmed by a review of the company's postmarketing surveillance data and in studies with validated clinical diagnoses".
Using Spain's CHS prescription claims database, the retrospective cohort study investigated elderly patients (>65 years of age) who initiated treatment with gabapentin (n = 5402) or pregabalin (n=6053) between 1 January...