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Introduction
Dermatofibrosarcoma protuberans (DFSP) a locally aggressive soft tissue neoplasm with intermediate- to low-grade malignancy [1]. It is reported in the literature as early as 1890. Darier and Ferrand first described it in 1924 as a distinct cutaneous disease entity called progressive and recurring dermatofibroma. Hoffman officially coined the term dermatofibrosarcoma protuberans in 1925 [1]. Pathologically this tumor is characterized in its early stage by large, spindle-shaped nuclei which are embedded fairly uniformly in the collagen stroma, parallel to the skin surface and infiltrating into the subcutaneous tissue in the honeycomb pattern. There is absence of cellular atypia, and mitoses are rare. In the nodular stage, there are irregular, short, intersecting bands of tumor cells forming a storiform pattern. Also typical are cells radiating from a central hub of fibrous tissue forming a cartwheel pattern. Occasionally, DFSP may show focal fibrosarcomatous changes with a characteristic herringbone pattern [1].The tumor is diffusely positive for CD34. There are several histological...