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In a retrospective study of 66 patients, five patients [ages and sexes not stated] were described who developed nocturnal enuresis, appeared sedated, eosinophilia, yellowish skin discolouration, elevated liver enzymes, stomach pain, adynamic, floppy or not able to walk during treatment with cannabidiol for refractory epilepsy [routes and times to reactions onsets not stated; not ail outcomes stated].
Patient 1: The patient initially started receiving cannabidiol 1-3 mg/kg/day. Cannabidiol crystalline powder was mixed into an oily solution containing cannabidiol 100mg per 1mL. Later, the dose was increased to 20 mg/kg/day. The patient became adynamic, floppy and was...