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Abstract
[...]the rate of small cell carcinoma, a subtype associated with a very poor prognosis, was 4.4%, which is greater than expected in the overall cervical cancer group (expected, <3%).7 Third, and perhaps most important, the 5-year survival rate in the entire patient group (women aged 35 years or under) in the study by Pelkofski et al3 was surprisingly low. [...]PARP inhibitors offer new treatment options, as up-regulation of PARP has been demonstrated in cervical cancer cells.