Correction to: Surfen and oxalyl surfen decrease tau hyperphosphorylation and mitigate neuron deficits in vivo in a zebrafish model of tauopathy

Abstract

Rights and permissions Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. Fig. 1 figure1 Surfen and oxalyl surfen are well tolerated by Tg [HuC::hTauP301L; DsRed] embryos. a Chemical structure of Surfen (1,3-bis(4-amino-2-methylquinolin-6-yl) urea), oxalyl surfen (N1,N2- bis(4-amino-2-methylquinolin-6-yl)oxalamide) and hemisurfen (1-(4-amino-2-methylquinolin-6- yl)urea). b Phenotypic analysis of 72 hpf wild-type (WT) and Tg [HuC::hTauP301L; DsRed] (hTauP301L) embryos incubated for 2 days in E3 medium containing 1% DMSO (hTauP301L + 1% DMSO), 80 mM LiCl (hTauP301L + LiCl), 3 μM surfen (hTauP301L + surfen), 2 μM oxalyl surfen (hTauP301L + oxalyl surfen) or 3 μM hemisurfen (hTauP301L + hemisurfen), showed that embryonic development is not impaired by the treatments. Magnification × 40. c Survival rate of 72 hpf wild-type (WT) and Tg [HuC::hTauP301L; DsRed] (hTauP301L) embryos incubated for 2 days in E3 medium containing 1% DMSO (hTauP301L + 1% DMSO), 80 mM LiCl (hTauP301L + LiCl), 3 μM surfen (hTauP301L + surfen), 2 μM oxalyl surfen (hTauP301L + oxalyl surfen), or 3 μM hemisurfen (hTauP301L + hemisurfen), demonstrated that embryonic mortality was not significantly increased by treatments (n = 250, P > 0.05, Student’s t test) Full size image The correct figure has been included in this correction, and the original article has been corrected.