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Abstract
The incidence of diabetes is increasing, but that of diabetic retinopathy is falling, probably owing to better management of glucose levels, lipid abnormalities, and hypertension. Clinical trials of VEGF and PPAR-α inhibitors are improving vision and providing insights into pathogenesis.
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1 From the Departments of Ophthalmology and Visual Sciences and Molecular and Integrative Physiology, University of Michigan Medical School, Ann Arbor (D.A.A., T.W.G.); and the Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison (R.K.).





