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A 26-year-old woman developed cardiac arrest, dysrhythmia, bradycardia, prolonged QTc interval, hypotension, polymorphic ventricular tachycardia and sustained a fall following loperamide toxicity secondary to abuse of loperamide at overdose. Additionally, she exhibited lack of efficacy with dopamine for bradycardia and hypotension.
The woman had a history of methadone use for opioid use disorder (OUD). She collapsed in front of her family after excessive consumption of loperamide (80-120 mg/day) [route not stated]. During emergency medical services transport, she developed a cardiac arrest and a wide complex dysrhythmia.
Initially, the woman was resuscitated with...