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Abstract
[...]the study was undertaken to know the effect of cigarette smoke on cognitive functions in young healthy adults. [16,17] Smoking causes pathophysiological changes in the brain[18] including oxidative damage, pro-inflammatory response, pro-atherosclerotic injury, thrombotic injury, interrupts blood-brain barrier, and disorganizes cell to cell junctions. [...]cigarette smoke alters the brain structures such as thinner frontal cortical areas, frontal gray matter aberrations, and decrease insulabased functional connectivity between orbitofrontal cortex, superior frontal gyrus, temporal lobe, and insula. [23] The limitation of our study, it was of short duration study and included a small sample size. [...]smokers can be classified as mild, moderate, and severe based on the packyears of cigarettes when a large cross-sectional study is done. [...]similar studies can be conducted in female smokers also to evaluate their cognitive performance as the number of female smokers has also increased in metropolitan cities like Bangalore.
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