It appears you don't have support to open PDFs in this web browser. To view this file, Open with your PDF reader
Abstract
Methamphetamine (METH) is an addictive drug causes toxicity and degeneration in the brain. Several evidence have demonstrated that METH toxicity results oxidative stress that regulate an intracellular signaling cascade that leads to cell death. In this paper we studied the effect of METH on calcium levels because of its great importance on human health. Calcium, is a messenger of extracellular signals in a great variety of cells; it regulates several neuronal functions, such as neurotransmitter synthesis and release, neuronal excitability, phosphorylation. Calcium is also involved in long-term processes, like memory. As well, we highlighted sodium levels to find out the main course in nerve function and to keep body fluids in balance.
The study was conducted on eighty people divided into three groups, thirty non addicted men as a control group(G1), taking into account and excluding, cigarette smoking, age, social and cultural conditions, and chronic diseases, also thirty people addicted to methamphetamine(G2), and twenty people addicted to methamphetamine and other narcotic substances (mix)(G3), whose ages ranged between (15-45) years and the period of methamphetamine abuse ranged between (1-7) years.
Calcium levels were highly significant in addicts group (P < 0.05), as compared to non addicts group. as well, when dividing by age, Calcium level were higher in METH and MIX addicts group (A2) as compared to addicts group (A1) and (A3) (P >0.05). Also, Calcium level were higher in METH and MIX addicts group (D3) as compared to addicts group (D1) and (D2) (P >0.05). We have noticed Increased duration of abuse Increases calcium levels. In addition to, Sodium levels were highly significant in addicts group (P < 0.05), as compared to non addicts group. During the study, it was found that age had an effect on sodium levels, Sodium level were higher in METH addicts group (A1) as compared to addicts group (A2) and (A3) (P> 0.05). While, Sodium level were higher in MIX addicts group (A2) as compared to addicts group (A1) and (A3) (P> 0.05). As well, Sodium level were higher in METH and MIX addicts group (D2) as compared to addicts group (D1) and (D3) (P> 0.05). Indeed, the difference in the duration of the abuse affects the sodium levels.
You have requested "on-the-fly" machine translation of selected content from our databases. This functionality is provided solely for your convenience and is in no way intended to replace human translation. Show full disclaimer
Neither ProQuest nor its licensors make any representations or warranties with respect to the translations. The translations are automatically generated "AS IS" and "AS AVAILABLE" and are not retained in our systems. PROQUEST AND ITS LICENSORS SPECIFICALLY DISCLAIM ANY AND ALL EXPRESS OR IMPLIED WARRANTIES, INCLUDING WITHOUT LIMITATION, ANY WARRANTIES FOR AVAILABILITY, ACCURACY, TIMELINESS, COMPLETENESS, NON-INFRINGMENT, MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE. Your use of the translations is subject to all use restrictions contained in your Electronic Products License Agreement and by using the translation functionality you agree to forgo any and all claims against ProQuest or its licensors for your use of the translation functionality and any output derived there from. Hide full disclaimer
Details
1 Ministry of interior/Federal security agency/ Border guard force command, Baghdad, Iraq