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© 2004 Chengde Mao. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Citation: Mao C (2004) The Emergence of Complexity: Lessons from DNA. PLoS Biol 2(12): e431. doi:10.1371/journal.pbio.0020431
Abstract
Given the diversity of the DNA sequences, we can easily engineer a large number of pairs of DNA duplexes that associate with each other with sequence specificity and in a well-defined fashion. Two neighboring duplexes are joined by two crossovers, which prevent any duplex from twisting against its neighbor duplex. [...]the interhelical angles become fixed at 0°. [...]of this design, regularly ordered 2D arrays have formed (Figure 2).
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