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ABSTRACT:
Medicinal plants have played an important role throughout the world in treating and preventing human diseases, commiphora wightii is an important medicinal plant of herbal heritage of India. Guggul is obtained from commiphora mukul which belong to the Family, Burseraceae . C. mukul occurs in north east Africa, Somali and southern Arabia , in India it is found in Gujrat, Mysore , Bengal, M. Pradesh , Desert of Rajastasthan a list of few Commiphora species C. Mukul, C. Myrrh , C. Stocksiana Engl, C. Caudate Engl. etc, Guggul tree is small ,1.2-1.8 m high. Each plant yield about one kilogram of the product which is collected in cold Season, isolation of guggul sterons , extract with EtOAC yield soluble fraction and insoluble fraction, soluble fraction consist of 45% gum resin while 55% insoluble fraction contains carbohydrate, there is no any therapeutic property reported. Guggul lipid has active ingredients like Ketosteroids cis and trans is also known as sterones. guggulsterone-I, II, III, IV, V, VI, myrcene, dimyrcene, bioactive compounds in extract of mukul reported are dimyrcene, 15 α- camphorene. 16 linoleic, oleic, stearic, palmitic acid, sitosterol etc. It is therapeutically used in obesity hyperlipidaemia, arthritis, coronary thrombosis, cardiac disorders, diabetes, tumours, thyroid disorders, hepatic obstructions and weakness pharyngitis etc. Marketed formulation of Guggul triphala Guggul, Yougaraja Guggul, kaishora gugguln, Navaka guggul etc.
KEYWORDS: Commiphora mukul, Chemistry, Guggul lipid, Therapeutic uses.
INTRODUCTION:
Medicinal plants have played an important role throughout the world in treating and preventing human diseases. The different medicinal plants such as arid zone plants, herbal plants and some shrubs have the potential role in the prevention and treatment of human diseases1.
Commiphora wightii popular by its vernacular name Guggulu is one of most important medicinal plant of traditional system of medicine and also having a nice status in modern research and drug system. It is the source of valuable oleo-gum-resin known as Guggulu gum. Guggulu gum has many medicinal and non medicinal properties2. Gugulipid (GL, guggul, guggal, or gugul lipid) is the ethyl acetate extract of gum guggul resin (raw material) that is harvested directly from the Commiphora mukul tree (family name: Burseraceae; synonyms: Hook, Bandari, Balsamodendron mukul, and Commiphora Wightii)3. In Indian ethno medicine, this plant is locally known as guggulu,...