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Int J Legal Med (2009) 123:495501 DOI 10.1007/s00414-009-0373-4
ORIGINAL ARTICLE
Forensic and phylogeographic characterization of mtDNA lineages from northern Thailand (Chiang Mai)
Bettina Zimmermann & Martin Bodner & Sylvain Amory & Liane Fendt &
Alexander Rck & David Horst & Basil Horst & Torpong Sanguansermsri &
Walther Parson & Anita Brandsttter
Received: 25 May 2009 /Accepted: 13 August 2009 /Published online: 2 September 2009 # Springer-Verlag 2009
Abstract The immigration of diverse ethnic groups over the past centuries from surrounding countries into Thailand left footprints in the genetic composition of Thai mitochondrial DNA (mtDNA) lineages. The entire mtDNA control region (1,122 bp) was typed in 190 unrelated male volunteers from the northern Thailand province of Chiang Mai following highest quality standards. For a more precise haplogroup classification, selected single nucleotide polymorphisms from the mtDNA coding region were geno-typed. We found several new, so far undescribed mtDNA lineages. Quasi-median networks were constructed for visual-isation of character conflicts. The data were put into population-genetic relationships with other Southeast Asian populations. Although the frequencies of the Thai haplogroups were characteristic for Southeast Asia in terms of haplotype
composition and genetic structure, the Thai population was significantly different from other Southeast Asian populations. This necessitates establishing regional databases, especially for forensic applications. The population data have been submitted to the EMPOP database (http://www.empop.org
Web End =www.empop.org ) and will be available on publication.
Keywords mtDNA population data . Southeast Asia . Network analysis . Haplogroup assignment . Phylogeographic analyses . Forensic science
Introduction
The Kingdom of Thailand is located in the heart of Southeast Asia. Due to its geographical location, Thai culture has always been under strong influence from China and India. Thailand is the only Southeast Asian country
Electronic supplementary material The online version of this article (doi:http://dx.doi.org/10.1007/s00414-009-0373-4
Web End =10.1007/s00414-009-0373-4 ) contains supplementary material, which is available to authorized users.
B. Zimmermann : M. Bodner : S. Amory : L. Fendt :
W. Parson (*)
Institute of Legal Medicine, Innsbruck Medical University, Mllerstrasse 44,Innsbruck, Austriae-mail: [email protected]
S. AmoryLaboratory of Molecular Anthropobiology, Institute of Legal Medicine,Strasbourg, France
S. AmoryInternational Commission on Missing Persons, Sarajevo, Bosnia and Herzegovina
A. RckInstitute of Mathematics, University of Innsbruck, Innsbruck, Austria
D. HorstPathologisches Institut, Ludwig-Maximilians-Universitt, Munich, Germany
B. HorstDepartment of Surgical Pathology,...