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Farhana Tahseen Taj [1] and Divya Vupperla [2] and Prarthana B. Desai [1]
Academic Editor: Jacek Cezary Szepietowski
1, Department of Dermatology, Venereology & Leprosy, Jawaharlal Nehru Medical College and KLE’s Dr. Prabhakar Kore Hospital and Medical Research Centre, Belgaum, Karnataka 590 010, India, jnmc.edu
2, Department of Dermatology, Venereology & Leprosy, Government District Headquarters Hospital, Khammam, Andhra Pradesh 507 002, India
Received Sep 1, 2017; Accepted Nov 8, 2017
This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
1. Introduction
Granulosis Rubra Nasi (GRN) is also known as “Acne papulo-rosacea of the nose.”. In 1901, a German dermatologist, Jadassohn, had described the first case of GRN as “Nasi hyperhidrotic Erythematosa micropapules Dermatosis Infantum” [1]. It is an inflammatory dermatosis involving eccrine sweat glands of central face and clinically presents with hyperhidrosis, erythema, papules, pustules, and vesicles. Rarely small comedo like lesions may be present [2].
It is usually limited to the front and sides of the nose. It may also affect the eyebrow, upper lip, and cheek. Presentation is common in childhood with a peak age of presentation at 7–12 years, but adolescent and adult onset is also possible. It has a chronic course and resolves at puberty without any sequelae. It is described as a focal form of hyperhidrosis which differs from the other forms, as it does not depend on the hypothalamic or emotional stimuli [3].
2. Case Report
A 33-year-old male patient presented with asymptomatic lesion over nose since 2 years to the outpatient department of dermatology and leprosy. The patient gave no history of any treatment taken before. There was no history of any fluid or cheesy material coming out of the lesions and no history of itching or burning (Figure 1). Clinically, we made a diagnosis of Granulosis Rubra Nasi, Lymphangioma Circumscriptum, Nevus Comedonicus, and sebaceous gland hyperplasia.
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A biopsy of the skin lesion was done. The histopathology report showed epidermal hyperplasia with spongiosis. Dermis shows dilated eccrine sweat glands. The infundibular and sebaceous ducts are plugged with stratum corneum and villous hair follicles. There is moderately peri-infundibular infiltrate of...