Content area
Full Text
European Journal of Human Genetics (2016) 24, 1650
& 2016 Macmillan Publishers Limited, part of Springer Nature. All rights reserved 1018-4813/16
http://www.nature.com/ejhg
Web End =www.nature.com/ejhg
BOOK REVIEW
Hereditary hearing loss: how to keep track at the extreme end of genetic and phenotypic variability
Hereditary Hearing Loss and Its Syndromes Third Edition Edited by: Helga V Toriello, Shelley D SmithISBN: 9780199731961Published by: Oxford University PressPrice: 130.00/$ 200.00
European Journal of Human Genetics (2016) 24, 1650; doi:http://dx.doi.org/10.1038/ejhg.2016.67
Web End =10.1038/ejhg.2016.67
Of all monogenic conditions, hearing loss is of unparalleled genetic heterogeneity maybe with the only exception of retinal degeneration. The hereditary hearing loss homepage (http://hereditaryhearingloss.org
Web End =http://hereditaryhearingloss.org ) currently lists about 100 genes for non-syndromic deafness (the term comprehensively used for all degrees of hearing impairment in the scientic literature), and, in addition, deafness is part of more than 400 genetic syndromes. The pace at which novel causative genes are being identied has accelerated signicantly since genomewide mapping,...