Content area

Abstract

High-throughput screening (HTS) has been postulated in several quarters to be a contributory factor to the decline in productivity in the pharmaceutical industry. Moreover, it has been blamed for stifling the creativity that drug discovery demands. In this article, we aim to dispel these myths and present the case for the use of HTS as part of a proven scientific tool kit, the wider use of which is essential for the discovery of new chemotypes.

Details

Title
Impact of high-throughput screening in biomedical research
Author
Macarron, Ricardo; Banks, Martyn N; Bojanic, Dejan; Burns, David J; Cirovic, Dragan A; Garyantes, Tina; Green, Darren V S; Hertzberg, Robert P; Janzen, William P; Paslay, Jeff W; Schopfer, Ulrich; Sittampalam, G Sitta
Pages
188-95
Publication year
2011
Publication date
Mar 2011
Publisher
Nature Publishing Group
ISSN
14741776
e-ISSN
14741784
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
854127146
Copyright
Copyright Nature Publishing Group Mar 2011