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In the present investigation the author intend to study the sub lethal and lethal effect of arsenic in presence of chelating agent (selenium) on biochemical compartmentation of phosphoglucomutase in various brain regions (cerebrum, diencephalon, cerebellum and medulla oblongata) in three phylogentically and onto-genetically different fish species i.e. Labeo rohita (Ham), Clarias batrachus (Linn) and Channa punctatus (Bloch) under acute studies from a tropical environment.
The variation in the above said enzyme subjected to sub-lethal concentration of arsenic in presence of chelating agent (selenium), were recorded the less fall in various brain region than the one exposed directly to sub-lethal concentration of arsenic educates that the chelating agent (selenium) has the detoxification ability and various changes of enzyme levels in different brain regions of three fresh water teleost.
INTRODUCTION
Water pollution is a major problem in many parts of India and is increasing day-byday around industrial and urban centers. Various environmental pollutants such as heavy metals, pesticides fertilizers, and sewage contaminate fresh water system. Heavy metals, on reaching aquatic ecosystems, pose a serious threat to the biota due to their stable and persistent existence. (Palaniappan et al., 2008).
Heavy metal contamination in environment is one of the most important problems world wide. It cannot only destroy through biological degradation, but heavy metals also have ability to accumulate for a long time leading to deterious effect on the aquatic ecosystem and consequently possess serious health complications in human through food chain. (Palipoch et al., 2011)
Fishes are often at the top of the aquatic food chain and may concentrate large amount of metals from the water. These metals accumulate in fish organs, causing serious health hazard to humans.
Fish are usually considered as organism of choice for assessing the effects of environmental pollution on aquatic ecosystem (Gernofer et al., 2001) lead has many undesired effect on humans and animals, including neurological, behavioral, respiratory, visual, growth retardation, hematological immunological, renal, hepatic (Dahia 2010).
Levels of arsenic are higher in the aquatic environment than in most areas of land as it is fairly water soluble and may be washed out of arsenic bearing rocks (Edmonds and Er. Francesconi, 1993.)
Fishes are sensitive to contaminations of water and pollutants may significantly damage the organs of these animals. Unlike mammals,...