Late onset autism and anti-NMDA-receptor encephalitis

Abstract

The neurological diagnosis was atypical childhood epilepsy with centrotemporal spikes, for which oral corticosteroids and antiepileptic drugs were prescribed. Childhood disintegrative disorder, early onset schizophrenia, and late onset autism often share a fi nal common pathway: previous normal development, followed by sudden neuropsychiatric regression of social interaction and communication skills, and a decline in intelligence and daily activities.1 The disorders are sometimes misrecognised and collectively called as autistic disorder.