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A 29-year-old woman developed rosacea-like facial rash during treatment with metformin off-label.
In February 2012, the woman was identified with impaired glucose tolerance, insulin-resistance and subclinical hypothyroidism and started receiving metformin [dosage and route not stated]. After 2 days of treatment, she observed intense pruritus and burning in the center of her face. In about 1 month, her skin rash worsened and the eruption involved her...