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Abstract
Michael Lesch was a medical student working at Johns Hopkins Hospital in Baltimore, MD, USA, when he and his mentor, William Nyhan, identified a rare inherited disorder that now bears their names. Lesch had attended Columbia University in New York before entering Johns Hopkins School of Medicine, Baltimore, MD. After specialising in cardiology, he held a series of increasingly prestigious administrative posts, beginning as chief of cardiology at Northwestern University's medical school in Chicago.