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A 78-year-old man with osteoarthritis developed alteration of his mental state with confusion, delirium and agitation during treatment with oxycodone/paracetamol [acetaminophen] after undergoing a right total knee arthroplasty.
The man, who had an extensive medical history, received postoperative morphine patient-controlled analgesia along with desipramine, furosemide, metformin and ciprofloxacin. He subsequently developed minor mental status changes, predominantly confusion. Morphine and...